ArticleFish physiology and biochemistry2010
Metallothionein biosynthesis as a detoxification mechanism in mercury exposure in fish, spotted scat (Scatophagus argus).
Article in Fish physiology and biochemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 45 citations in OpenAlex.
- Acute toxicity of mercury in response to metallothionein expression and oxidative and cellular metabolic stress in Barbonymus gonionotus.Scientific reports · 2025Article
- Heavy Metal Bioaccumulation in Highly Consumed Pelagic and Benthic Fish and Associated Health Risk.Biological trace element research · 2024Article
- Mercury accumulation and biomarkers of exposure in two popular recreational fishes in Hawaiian waters.Ecotoxicology (London, England) · 2023Article
- Antarctic Fish as a Global Pollution Sensor: Metals Biomonitoring in a Twelve-Year Period.Frontiers in molecular biosciences · 2021Article
- Metal loads and biomarker suite responses in a tropical carnivorous fish indicative of anthropogenic impacts in a Southeastern Brazilian lagoon.Environmental monitoring and assessment · 2018Article
- Metallothionein from Wild Populations of the African Catfish Clarias gariepinus: From Sequence, Protein Expression and Metal Binding Properties to Transcriptional Biomarker of Metal Pollution.International journal of molecular sciences · 2017Article
- Are higher blood mercury levels associated with dry eye symptoms in adult Koreans? A population-based cross-sectional study.BMJ open · 2016Article
- Effects of Two Sublethal Concentrations of Mercury Chloride on the Morphology and Metallothionein Activity in the Liver of Zebrafish (Danio rerio).International journal of molecular sciences · 2016Article
- Article
- Evaluation of the use of metallothionein as a biomarker for detecting physiological responses to mercury exposure in the bonnethead, Sphyrna tiburo.Fish physiology and biochemistry · 2014Article
- Polycyclic aromatic hydrocarbons in the coastal sea water, the surface sediment and Mudskipper Boleophthalmus dussumieri from coastal areas of the Persian Gulf: source investigation, composition pattern and spatial distribution.Journal of environmental health science & engineering · 2014Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is of crucial importance to study on the biomarkers types to assess the specification of the pollutants and health status of marine ecosystems in environmental evaluation projects. In this respect, total metallothionein biosynthesis and mercury bioaccumulation in the liver and gills under acute mercury exposure were investigated in fish, Scat (Scatophagus argus). Spotted scat was exposed to different mercury concentrations (0, 10, 20, 30) for 24, 48, 72 h. Total MT levels were determined by enzyme-linked immunosorbent assay (ELISA) method. Mercury contents were determined through cold vapor atomic absorption spectrometry (CVAAS). Induction of MT during exposure was tissue specific, displaying different response pattern in gills and liver. Mercury accumulated in liver much higher than in gills and the latter also showed lower MT level (P<0.05). MT biosynthesis in liver showed a significant (P<0.05) increase after exposure to different mercury concentration with increase in exposure time, whereas total MT content did not significantly (P>0.05) change in gills except for 72 h exposure at 30 μg l(-1). Nonetheless, the relationship between MT biosynthesis and Mercury bioaccumulation in both tissues was significant (P<0.05). The results suggest that this form of MT in S. argus was Hg inducible and could be extended as a biomarker of mercury pollution in marine ecosystems.
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