ArticleInternational journal of legal medicine2010
qPCR and mtDNA SNP analysis of experimentally degraded hair samples and its application in forensic casework.
Article in International journal of legal medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Forensic Characterization, Genomic Variability and Ancestry Analysis of Six Populations from Odisha Using mtDNA SNPs and Autosomal STRs.Biochemical genetics · 2025Article
- A multi-level overview of the hair decomposition process.International journal of legal medicine · 2025Review
- Genetic polymorphism analysis of mitochondrial DNA from Chinese Xinjiang Kazak ethnic group by a novel mitochondrial DNA genotyping panel.Molecular biology reports · 2019Article
- Genetic polymorphisms of 54 mitochondrial DNA SNP loci in Chinese Xibe ethnic minority group.Scientific reports · 2017Article
- The SNPforID Assay as a Supplementary Method in Kinship and Trace Analysis.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2012Article
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Authors and funding
4 authors.
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Abstract
A mitochondrial DNA (mtDNA) quantification PCR (qPCR) method was developed and applied in a study with experimentally degraded hair samples (first study) and in a criminal case (second study). In the first study, the amount of detectable mtDNA decreased drastically after an incubation time of 1 month on a moist tissue in a heating cabin at 37 degrees C. In the second study, when the qPCR assay showed positive quantification results, further analysis of 32 mtDNA single-nucleotide polymorphisms (SNPs) via SNaPshot technique was always possible, indicating that successful mtDNA SNP analysis of forensic samples can be guaranteed by pre-screening samples with the qPCR described here.
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