ArticleParasitology research2010
Pathogenic potential of Blastocystis hominis in laboratory mice.
Article in Parasitology research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Investigation ofAfrican health sciences · 2025Article
- Molecular Identification and Genotyping ofArchives of Razi Institute · 2025Article
- Effect ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024Article
- The influence of plant extracts on viability of ST3 and ST7 subtypes of Blastocystis sp.Gut pathogens · 2024Article
- Association of Blastocystis ST6 with higher protease activity among symptomatic subjects.BMC microbiology · 2021Article
- Article
- Exploring Micro-Eukaryotic Diversity in the Gut: Co-occurrence ofFrontiers in microbiology · 2020Article
- Molecular characterization of Blastocystis subtypes in HIV-positive patients and evaluation of risk factors for colonization.BMC infectious diseases · 2019Article
- Molecular epidemiology of Blastocystis sp. in dogs housed in Italian rescue shelters.Parasitology research · 2019Article
- Extra-enteric Blastocystis infection in a duck.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2019Article
- Molecular characterization of Blastocystis in cattle in Turkey.Parasitology research · 2019Article
- Prevalence, Molecular Identification, and Risk Factors forFrontiers in microbiology · 2019Article
- Epidemiology and Prevalence ofThe American journal of tropical medicine and hygiene · 2017Article
- Immunopathological assessments of human Blastocystis spp. in experimentally infected immunocompetent and immunosuppresed mice.Parasitology research · 2016Article
- PATHOGENICITY OF Blastocystis sp. TO THE GASTROINTESTINAL TRACT OF MICE: RELATIONSHIP BETWEEN INOCULUM SIZE AND PERIOD OF INFECTION.Revista do Instituto de Medicina Tropical de Sao Paulo · 2015Article
- Genetic diversity of blastocystis isolated from cattle in khorramabad, iran.Jundishapur journal of microbiology · 2015Article
- Blastocystis sp. in splenic cysts: causative agent or accidental association? A unique case report.Parasites & vectors · 2014Article
- Update on the pathogenic potential and treatment options for Blastocystis sp.Gut pathogens · 2014Review
- A rat model to study Blastocytis subtype 1 infections.Parasitology research · 2013Article
- Blastocystosis in patients with gastrointestinal symptoms: a case-control study.BMC gastroenterology · 2012Article
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2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Blastocystis hominis is a ubiquitous enteric protozoan whose pathogenic potential is still controversial. This study was carried out to clarify the pathogenecity of B. hominis infection and to study the proper number of parasites for mice infection. A total of 15 albino mice were orally inoculated with B. hominis and divided according to the inoculums, 10(2), 10(5), and 4 x 10(7) B. hominis forms/100 microl saline, into three groups consisting of five mice each, GI, GII GIII, respectively. In addition with group IV (uninfected control) consisting of five mice. All mice were sacrificed 2 weeks post-infection. The results revealed that all mice of GIII and two mice of GII got the infection while all mice of GI showed a completely negative result. Histopathological examination of large intestine on highly infected group (GIII) showed that B. hominis infiltrated the lamina propria, the submucosa, and the muscle layers in the form of collection of vacuolar forms. This was accompanied by active colitis with infiltration of mixed inflammatory cells. In conclusion, this study revealed that large number of B. hominis is essential for oral infection of mice and that vacuolar forms of B. hominis can invade the lamina propria, the submucosa, and even the muscle layers.
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