Evidence map›Paper›PMID 20498294›Full record

ReviewPsychosomatic medicine2010

Neurobiological pathways linking socioeconomic position and health.

Peter J Gianaros, Stephen B Manuck

Abstract readReview
In one paragraph

Review in Psychosomatic medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Trial
  2. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Peter J GianarosDepartment of Psychiatry, Thomas Detre Hall, University of Pittsburgh, Pittsburgh, PA 15213, USA. gianarospj@upmc.edu
Stephen B Manuck

Funding

Substrates of Threat and Reward Sensitivity and CVD RiskP01HL040962 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GIANAROS, PETER J · 1988 to 2022
$31.1M
Neurobiological pathways linking stress and emotion to atherosclerosisR01HL089850 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GIANAROS, PETER J · 2008 to 2016
$4.7M
NEUROGENETICS, SEROTONIN, AND HUMAN AGGRESSIONR01HL065137 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MANUCK, STEPHEN B · 2000 to 2003
$1.5M
Functional Organization of Cardiovascular ReactivityK01MH070616 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GIANAROS, PETER J · 2004 to 2008
$593k
NHLBI NIH HHS P01 HL040962NHLBI NIH HHS P01 HL40962NHLBI NIH HHS R01 HL065137NHLBI NIH HHS R01 HL089850NIMH NIH HHS K01 MH070616
6 · The paper itself

Abstract

Across individuals, risk for poor health varies inversely with socioeconomic position (SEP). The pathways by which SEP affects health have been viewed from many epidemiological perspectives. Central to these perspectives is the notion that socioeconomic health disparities arise from an interplay between nested, recursive, and cumulative environmental, social, familial, psychological, behavioral, and physiological processes that unfold over the life span. Epidemiological perspectives on socioeconomic health disparities, however, have not yet formally integrated emerging findings from neuropharmacological, molecular genetic, and neuroimaging studies demonstrating that indicators of SEP relate to patterns of brain neurotransmission, brain morphology, and brain functionality implicated in the etiology of chronic medical conditions and psychological disorders. Here, we survey these emerging findings and consider how future neurobiological studies in this area can enhance our understanding of the pathways by which different dimensions of SEP become embodied by the brain to influence health throughout life.

Indexed as

Health Status DisparitiesSocial ClassBrainChronic DiseaseHealthcare DisparitiesHumansHydroxyindoleacetic AcidMental DisordersNeurobiologyResearchResearch DesignSerotonin Plasma Membrane Transport ProteinsSynaptic TransmissionHydroxyindoleacetic AcidSerotonin Plasma Membrane Transport Proteins

Identifiers

PMID20498294
PMCPMC2903752

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.