ArticleProceedings of the National Academy of Sciences of the United States of America2010
Control of dissected leaf morphology by a Cys(2)His(2) zinc finger transcription factor in the model legume Medicago truncatula.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 102 citations in OpenAlex.
- Breeding of a Multifoliolate Alfalfa Population Using CRISPR/Cas9-Generated Mutants and Evaluation of Agronomic Traits and Nutritive Value.Plants (Basel, Switzerland) · 2026Article
- Building beauty: Understanding how hormone signaling regulates petal patterning and morphogenesis.The Plant journal : for cell and molecular biology · 2025Review
- QTL mapping and BSR-seq revealed loci and candidate genes associated with the sporadic multifoliolate phenotype in soybean (Glycine max).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- GRAS transcription factor PINNATE-LIKE PENTAFOLIATA2 controls compound leaf morphogenesis in Medicago truncatula.The Plant cell · 2024Article
- Mechanism of the Pulvinus-Driven Leaf Movement: An Overview.International journal of molecular sciences · 2024Review
- Control of compound leaf patterning by MULTI-PINNATE LEAF1 (MPL1) in chickpea.Nature communications · 2023Article
- Review
- Biological and genomic analysis of a symbiotic nitrogen fixation defective mutant inFrontiers in plant science · 2023Article
- The upregulated LsKN1 gene transforms pinnately to palmately lobed leaves through auxin, gibberellin, and leaf dorsiventrality pathways in lettuce.Plant biotechnology journal · 2022Article
- Leaf Development inGenes · 2022Review
- De novo phasing resolves haplotype sequences in complex plant genomes.Plant biotechnology journal · 2022Review
- Developmental Analysis of Compound Leaf Development inFrontiers in plant science · 2022Article
- BoALG10, an α-1,2 glycosyltransferase, plays an essential role in maintaining leaf margin shape in ornamental kale.Horticulture research · 2022Article
- Signatures of Transcription Factor Evolution and the Secondary Gain of Red Algae Complexity.Genes · 2021Article
- Rapid identification of mutations caused by fast neutron bombardment in Medicago truncatula.Plant methods · 2021Article
- The F-box protein MIO1/SLB1 regulates organ size and leaf movement in Medicago truncatula.Journal of experimental botany · 2021Article
- Expanding the Benefits ofFrontiers in plant science · 2021Article
- The Genetic Control of the Compound Leaf Patterning inFrontiers in plant science · 2021Review
- The 3-ketoacyl-CoA synthase WFL is involved in lateral organ development and cuticular wax synthesis in Medicago truncatula.Plant molecular biology · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant leaves are diverse in their morphology, reflecting to a large degree the plant diversity in the natural environment. How different leaf morphology is determined is not yet understood. The leguminous plant Medicago truncatula exhibits dissected leaves with three leaflets at the tip. We show that development of the trifoliate leaves is determined by the Cys(2)His(2) zinc finger transcription factor PALM1. Loss-of-function mutants of PALM1 develop dissected leaves with five leaflets clustered at the tip. We demonstrate that PALM1 binds a specific promoter sequence and down-regulates the expression of the M. truncatula LEAFY/UNIFOLIATA orthologue SINGLE LEAFLET1 (SGL1), encoding an indeterminacy factor necessary for leaflet initiation. Our data indicate that SGL1 is required for leaflet proliferation in the palm1 mutant. Interestingly, ectopic expression of PALM1 effectively suppresses the lobed leaf phenotype from overexpression of a class 1 KNOTTED1-like homeobox protein in Arabidopsis plants. Taken together, our results show that PALM1 acts as a determinacy factor, regulates the spatial-temporal expression of SGL1 during leaf morphogenesis and together with the LEAFY/UNIFOLIATA orthologue plays an important role in orchestrating the compound leaf morphology in M. truncatula.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.