Evidence map›Paper›PMID 20497228›Full record

ArticleFEMS microbiology letters2010

Identification of the long polar fimbriae gene variants in the locus of enterocyte effacement-negative Shiga toxin-producing Escherichia coli strains isolated from humans and cattle in Argentina.

Lucía Galli, Alfredo G Torres, Marta Rivas

Abstract read
In one paragraph

Article in FEMS microbiology letters, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
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  9. EHEC Adhesins.Microbiology spectrum
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lucía GalliServicio Fisiopatogenia, Departamento de Bacteriología, Instituto Nacional de Enfermedades Infecciosas-ANLIS 'Dr. Carlos G. Malbrán', Buenos Aires, Argentina. lgalli@anlis.gov.ar
Alfredo G Torres
Marta Rivas

Funding

Long Polar Fimbriae of Attaching and Effacing Escherichia coliR01AI079154 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI TORRES, ALFREDO G · 2009 to 2013
$1.9M
NIAID NIH HHS AI079154 -01A2NIAID NIH HHS R01 AI079154
6 · The paper itself

Abstract

The long polar fimbriae (Lpf) is one of few adhesive factors of Shiga toxin-producing Escherichia coli (STEC) and it is associated with colonization of the intestine. Studies have demonstrated the presence of lpf genes in several pathogenic E. coli strains, and classification of variants based on polymorphisms in the lpfA1 and lpfA2 genes has been adopted. Using a collection of Argentinean locus of enterocyte effacement (LEE)-negative STEC strains, we determined that the different lpfA types were present in a wide variety of serotypes with no apparent association between the types of lpfA1 or lpfA2 genes and the severity of human disease. The lpfA2-1 was the most prevalent variant identified, which was present in 95.8% of the isolates, and lpfA1-3 and lpfA2-2, proposed as specific biomarkers of E. coli O157:H7, were not found in any of the serotypes studied. The prevalence of lpf genes in a large number of strains is useful to understand the genetic diversity of LEE-negative STEC and to define the association of some of these isolates carrying specific lpf-variants with disease.

Indexed as

AnimalsArgentinaCattleCattle DiseasesEscherichia coli InfectionsEscherichia coli ProteinsFimbriae, BacterialGenetic VariationHumansPhosphoproteinsSerotypingShiga-Toxigenic Escherichia coliEscherichia coli ProteinsLEE protein, E coliPhosphoproteins

Identifiers

PMID20497228
PMCPMC2905465

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.