ArticleEvolution; international journal of organic evolution2010
Three selections are better than one: clinal variation of thermal QTL from independent selection experiments in Drosophila.
Article in Evolution; international journal of organic evolution, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Experimental Evolution in a Warming World: The Omics Era.Molecular biology and evolution · 2024Review
- Naturally segregating genetic variants contribute to thermal tolerance in a Drosophila melanogaster model system.Genetics · 2024Article
- Unveiling Subtle Geographical Clines: Phenotypic Effects and Dynamics of Circadian Clock Gene Polymorphisms.Biology · 2023Article
- Temperature, rainfall and wind variables underlie environmental adaptation in natural populations of Drosophila melanogaster.Molecular ecology · 2021Article
- Natural selection on sleep duration in Drosophila melanogaster.Scientific reports · 2020Article
- Genome-Wide Association Study of Circadian Behavior in Drosophila melanogaster.Behavior genetics · 2019Article
- Selection for long and short sleep duration in Drosophila melanogaster reveals the complex genetic network underlying natural variation in sleep.PLoS genetics · 2017Article
- Genetic Decoupling of Thermal Hardiness across Metamorphosis in Drosophila melanogaster.Integrative and comparative biology · 2017Article
- Comparative population genomics of latitudinal variation in Drosophila simulans and Drosophila melanogaster.Molecular ecology · 2016Article
- Keeping pace with climate change: what is wrong with the evolutionary potential of upper thermal limits?Ecology and evolution · 2012Article
- Adaptation of Drosophila to a novel laboratory environment reveals temporally heterogeneous trajectories of selected alleles.Molecular ecology · 2012Article
- Longitudinal trends in climate drive flowering time clines in North American Arabidopsis thaliana.Ecology and evolution · 2012Article
- Mutualism meltdown in insects: bacteria constrain thermal adaptation.Current opinion in microbiology · 2012Review
- Testing for causality in covarying traits: genes and latitude in a molecular world.Molecular ecology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
We report the results of two independent selection experiments that have exposed distinct populations of Drosophila melanogaster to different forms of thermal selection. A recombinant population derived from Arvin California and Zimbabwe isofemale lines was exposed to laboratory natural selection at two temperatures (T(AZ): 18°C and 28°C). Microsatellite mapping identified quantitative trait loci (QTL) on the X-chromosome between the replicate "Hot" and "Cold" populations. In a separate experiment, disruptive selection was imposed on an outbred California population for the "knockdown" temperature (T(KD)) in a thermal column. Microsatellite mapping of the "High" and "Low" populations also uncovered primarily X-linked QTL. Notably, a marker in the shaggy locus at band 3A was significantly differentiated in both experiments. Finer scale mapping of the 3A region has narrowed the QTL to the shaggy gene region, which contains several candidate genes that function in circadian rhythms. The same allele that was increased in frequency in the High T(KD) populations is significantly clinal in North America and is more common at the warm end of the cline (Florida vs. Maine; however, the cline was not apparent in Australia). Together, these studies show that independent selection experiments can uncover the same target of selection and that evolution in the laboratory can recapitulate putatively adaptive clinal variation in nature.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.