ReviewCurrent pain and headache reports2010
Migraine and epilepsy: a focus on overlapping clinical, pathophysiological, molecular, and therapeutic aspects.
Review in Current pain and headache reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.
- Association of ESR1 Polymorphisms with Susceptibility to Migraine: A Meta-Analysis and Trial Sequential Analysis.Current pain and headache reports · 2025Pooled it
- Causal influences of migraine on neuropsychiatric disorders: A 2-sample Mendelian randomization study.Medicine · 2025Article
- A cross-sectional, multicenter survey of the prevalence and influencing factors for migraine in epilepsy.Epilepsia open · 2024Article
- Primary Headache Is Related to Reduced Health-Related Quality of Life in Children with Epilepsy.Healthcare (Basel, Switzerland) · 2024Article
- Migraine and Epilepsy in Children: A Narrative Review of Comorbidity and Similar Treatment Option.Iranian journal of child neurology · 2024Review
- Case report: An EEG captured case of migralepsy/migraine aura-triggered seizures.Frontiers in neurology · 2022Article
- Headache in people with epilepsy.Nature reviews. Neurology · 2021Review
- Migraine: A Review on Its History, Global Epidemiology, Risk Factors, and Comorbidities.Frontiers in neurology · 2021Review
- Pain Modulation in WAG/Rij Epileptic Rats (A Genetic Model of Absence Epilepsy): Effects of Biological and Pharmacological Histone Deacetylase Inhibitors.Frontiers in pharmacology · 2020Article
- Clinical manifestations of hydropic ear disease (Menière's).European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019Article
- [Pain and epilepsy : A clinical, neuroanatomical and pathophysiological review].Schmerz (Berlin, Germany) · 2018Article
- Epilepsy and migraine-Are they comorbidity?Genes & diseases · 2018Review
- The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence.Frontiers in physiology · 2016Review
- Article
- Ictal epileptic headache revealing non convulsive status epilepticus in a case of eyelid myoclonia with absences.The journal of headache and pain · 2015Article
- Headache in epilepsy: prevalence and clinical features.The journal of headache and pain · 2015Article
- Genetic forms of epilepsies and other paroxysmal disorders.Seminars in neurology · 2014Review
- The enzymes of human diphosphoinositol polyphosphate metabolism.The FEBS journal · 2014Review
- Clinical course and seizure outcome of idiopathic childhood epilepsy: determinants of early and long-term prognosis.BMC neurology · 2013Article
- Genes and primary headaches: discovering new potential therapeutic targets.The journal of headache and pain · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The association of epilepsy and migraine has been long recognized. Migraine and epilepsy are both chronic disorders with episodic attacks. Furthermore, headache may be a premonitory or postdromic symptom of seizures, and migraine headaches may cause seizures per se (migralepsy). Migraine and epilepsy are comorbid, sharing pathophysiological mechanisms and common clinical features. Several recent studies identified common genetic and molecular substrates for migraine and epilepsy, including phenotypic-genotypic correlations with mutations in the CACNA1A, ATP1A2, and SCN1A genes, as well as in syndromes due to mutations in the SLC1A3, POLG, and C10orF2 genes. Herein, we review the relationship between migraine and epilepsy, focusing on clinical aspects and some recent pathophysiological and molecular studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.