ReviewClinical rheumatology2010
Etiopathogenesis of Behçet's disease with emphasis on the role of immunological aberrations.
Review in Clinical rheumatology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 84 citations in OpenAlex.
- Oral Lesions as the Primary Manifestations of Behçet's Disease: The Importance of Interdisciplinary Diagnostics-A Case Report.Biomedicines · 2023Article
- Increased T-bet/GATA-3 and ROR-γt /Foxp3 Ratios in Cerebrospinal Fluid as Potential Criteria for Definite Neuro-Behçet's Disease.Journal of clinical medicine · 2022Article
- The role of YKL-40 in the pathogenesis of autoimmune diseases: a comprehensive review.International journal of biological sciences · 2022Review
- Impact of disease activity on health related quality of life in patients with Behçet's disease: A cross-sectional study.Annals of medicine and surgery (2012) · 2020Article
- Dysregulation of glycerophospholipid metabolism during Behçet's disease contributes to a pro-inflammatory phenotype of circulating monocytes.Journal of translational autoimmunity · 2020Article
- Auto-immunity profile evaluation during different clinical manifestations of Behçet disease in Algerian patients: effect of corticosteroid treatment.Inflammopharmacology · 2019Article
- Influence of corticosteroid therapy on IL-18 and nitric oxide production during Behçet's disease.Inflammopharmacology · 2018Article
- Investigation of the role of interleukin-1 receptor antagonist VNTR variant on the Behçet's disease.European journal of rheumatology · 2018Article
- Hughes-Stovin Syndrome as an Outcome of Behçet Disease or as a Different Entity.The Korean journal of thoracic and cardiovascular surgery · 2018Article
- Plasma Saturated and Monounsaturated Fatty Acids in Behçet's Disease.The open rheumatology journal · 2018Article
- Novel markers of endothelial dysfunction and inflammation in Behçet's disease patients with ocular involvement: epicardial fat thickness, carotid intima media thickness, serum ADMA level, and neutrophil-to-lymphocyte ratio.Clinical rheumatology · 2016Article
- Article
- Anti-interferon alpha antibodies and autoantibodies in patients with Behçet's disease uveitis treated with recombinant human interferon alpha-2a.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2015Article
- Inflammation-related cytokine gene polymorphisms in Behçet's disease.Journal of inflammation research · 2015Article
- Genital aphthosis in Behçet's disease: is it associated with less eye involvement?Rheumatology international · 2014Article
- Current and future treatments for Behçet's uveitis: road to remission.International ophthalmology · 2014Review
- Immunopathogenesis of ocular Behçet's disease.Journal of immunology research · 2014Review
- Gene expression profiling and association studies implicate the neuregulin signaling pathway in Behçet's disease susceptibility.Journal of molecular medicine (Berlin, Germany) · 2013Article
- Differential diagnosis and management of Behçet syndrome.Nature reviews. Rheumatology · 2013Review
- Fc-Gamma Receptor 3B Copy Number Variation Is Not a Risk Factor for Behçet's Disease.International journal of rheumatology · 2012Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Behçet's disease (BD) is a chronic multisystemic inflammatory disorder of unknown origin consisting of oral aphthous ulcers, ocular symptoms, skin lesions, and genital ulcerations. It has many features in common with systemic vasculitides and is more prevalent in countries along the ancient Silk route. Immune-mediated mechanisms play a major role in the pathogenesis of the disease, and inflammatory mediators are also involved. BD is not considered to be an autoimmune disorder, and the character of the disease needs to be clarified. Immunological aberrations in BD have been extensively studied by many investigators; genetic factors have been related to disease susceptibility, but their exact role in the development of disease is uncertain. Environmental factors such as infectious agents have also been implicated in the etiology of BD. However, the etiopathogenesis of the disease remains to be elucidated. Factors involved in the immunopathogenesis of BD with emphasis on the role of immunological aberrations are analyzed in this review.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.