Trial reportClinical oral investigations2011
Periodontal therapy and risk for adverse pregnancy outcomes.
Trial report in Clinical oral investigations, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 8 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- The impact of scaling and root planning combined with mouthwash during pregnancy on preterm birth and low birth weight: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- Effect of Treating Periodontal Disease in Pregnant Women to Reduce the Risk of Preterm Birth and Low Birth Weight: An Umbrella Review.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Effects of different periodontal interventions on the risk of adverse pregnancy outcomes in pregnant women: a systematic review and network meta-analysis of randomized controlled trials.Frontiers in public health · 2024Pooled it
- Association of Chlorhexidine Use and Scaling and Root Planing With Birth Outcomes in Pregnant Individuals With Periodontitis: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- Treating periodontal disease for preventing adverse birth outcomes in pregnant women.The Cochrane database of systematic reviews · 2017Pooled it
- Influence of obesity on the outcome of non-surgical periodontal therapy - a systematic review.BMC oral health · 2016Pooled it
- Periodontal treatment for preventing adverse pregnancy outcomes: a meta- and trial sequential analysis.PloS one · 2015Pooled it
- Obstetric outcomes after treatment of periodontal disease during pregnancy: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2010Pooled it
- Non-Surgical Treatment of Periodontal Disease in a Pregnant Caucasian Women Population: Adverse Pregnancy Outcomes of a Randomized Clinical Trial.International journal of environmental research and public health · 2019Trial
- Effect of nonsurgical periodontal therapy and strict plaque control on preterm/low birth weight: a randomized controlled clinical trial.Clinical oral investigations · 2013Trial
- Design characteristics of studies evaluating the effect of non-surgical periodontal treatment on systemic health outcomes.Journal of periodontology · 2026Review
- Examining the association of maternal oral health experiences with adverse birth outcomes: findings from Virginia's PRAMS survey.BMC oral health · 2026Article
- Evaluation of the periodontal disease on oral microorganisms during pregnancy: A systematic review and meta-analysis.Journal of clinical and translational research · 2023Review
- Review
- Association between Maternal Periodontitis and Development of Systematic Diseases in Offspring.International journal of molecular sciences · 2022Review
- Periodontal Diseases and Adverse Pregnancy Outcomes: Review of Two Decades of Clinical Research.Oral health & preventive dentistry · 2021Review
- Maternal Supplementation of Low Dose Fluoride Alleviates Adverse Perinatal Outcomes Following Exposure to Intrauterine Inflammation.Scientific reports · 2019Article
- Article
- Periodontitis, cardiovascular disease and pregnancy outcome--focal infection revisited?British dental journal · 2014Review
- Relationship between maternal periodontal status and preterm low birth weight.Reviews in obstetrics & gynecology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periodontitis has been associated with adverse pregnancy outcomes. Results from intervention studies are few and controversial. The present study assessed the effects of non-surgical periodontal treatment in the occurrence of adverse pregnancy outcomes. Two hundred forty-six eligible women were randomly divided into two groups: periodontitis intervention (n = 122; undergoing non-surgical treatment during gestation) and periodontitis control (n = 124; not treated during gestation). Univariate analysis was performed and estimates of relative risk were reported. Data from 225 women were analyzed. No differences for preterm birth (p = 0.721), low birth weight (p = 0.198), and preterm low birth weight (p = 0.732) rates were observed. Relative risk estimates for preterm birth, low birth weight, and preterm low birth weight in the periodontitis intervention group were 0.915 (95% CI 0.561-1.493), 0.735 (95% CI 0.459-1.179), and 0.927 (0.601-1.431), respectively. Non-surgical periodontal treatment during the second semester of gestation did not reduce the risk for preterm birth, low birth weight, and preterm low birth weight.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.