Evidence map›Paper›PMID 20495576›Full record

ReviewNature reviews. Cancer2010

The colony-stimulating factors and cancer.

Donald Metcalf

Open access · bronzeAbstract readReview
In one paragraph

Review in Nature reviews. Cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 146 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Current state and future opportunities in granulocyte colony-stimulating factor (G-CSF).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  15. Review
  16. FasLAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  17. Review
  18. Mechanism of Emodin in the Treatment of Rheumatoid Arthritis.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  19. Frontiers in pharmacology · 2022
    Article
  20. Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Donald MetcalfThe Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia. metcalf@wehi.edu.au
Walter and Eliza Hall Institute of Medical Research · AU

Funding

Differentiation of Granulocytes and MacrophagesR37CA022556 · NCI · WALTER AND ELIZA HALL INST MEDICAL RES · PI METCALF, DONALD · 2005 to 2014
$2.3M
DIFFERENTIATION OF GRANULOCYTES AND MACROPHAGESR01CA022556 · NCI · WALTER AND ELIZA HALL INST MEDICAL RES · PI METCALF, DONALD · 1985 to 2004
$900k
NCI NIH HHS CA22556NCI NIH HHS R01 CA022556NCI NIH HHS R37 CA022556
6 · The paper itself

Abstract

The four colony-stimulating factors (CSFs) are glycoproteins that regulate the generation and some functions of infection-protective granulocytes and macrophages. Recombinant granulocyte-CSF (G-CSF) and granulocyte-macrophage-CSF (GM-CSF) have now been used to increase dangerously low white blood cell levels in many millions of cancer patients following chemotherapy. These CSFs also release haematopoietic stem cells to the peripheral blood, and these cells have now largely replaced bone marrow as more effective populations for transplantation to cancer patients who have treatment-induced bone marrow damage.

Indexed as

AnimalsAntineoplastic AgentsCell LineageColony-Stimulating FactorsHumansLeukopeniaNeoplasmsAntineoplastic AgentsColony-Stimulating Factors

Identifiers

PMID20495576
PMCPMC3345291
OpenAlexW2116436598

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.