Evidence map›Paper›PMID 20495000›Full record

ArticleBioinformatics (Oxford, England)2010

FuncBase: a resource for quantitative gene function annotation.

John E Beaver, Murat Tasan, Francis D Gibbons, Weidong Tian, Timothy R Hughes, Frederick P Roth

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Application of comparative biology in GO functional annotation: the mouse model.Mammalian genome : official journal of the International Mammalian Genome Society · 2015
    Article
  4. Article
  5. GeneMANIA prediction server 2013 update.Nucleic acids research · 2013
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

John E BeaverDepartment of Biological Chemistry & Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
Murat Tasan
Francis D Gibbons
Weidong Tian
Timothy R Hughes
Frederick P Roth

Funding

Genomic Analysis of Network Perturbations in Human DiseaseP50HG004233 · NHGRI · DANA-FARBER CANCER INST · PI VIDAL, MARC · 2007 to 2017
$31.6M
The C. elegans Interactome ProjectR01HG001715 · NHGRI · MASSACHUSETTS GENERAL HOSPITAL · PI HILL, DAVID E., ROTH, FREDERICK P · 1998 to 2010
$16.5M
TRIGEMINAL NERVE--CONTROL OF THE BRAIN VASCULATUREP01NS035611 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI MOSKOWITZ, MICHAEL A. · 1996 to 2011
$15.4M
Mapping the first half of the REFERENCE human binary protein interactomeU01HG001715 · NHGRI · DANA-FARBER CANCER INST · PI HILL, DAVID E., ROTH, FREDERICK P · 2012 to 2014
$5.4M
Patients undergoing alcohol septal ablation for hypertrophic cardiomyopathyU01HL081341 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI GERSZTEN, ROBERT E · 2005 to 2008
$5.3M
Resource ProjectU41HG001715 · NHGRI · DANA-FARBER CANCER INST · PI HILL, DAVID E. · 2015 to 2017
$4.7M
Computational Methods for Directed Functional GenomicsR01HG003224 · NHGRI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROTH, FREDERICK P · 2005 to 2010
$2.2M
MIGRAINE DRUG PROPHYLAXISR01NS054052 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI MOSKOWITZ, MICHAEL A. · 2006 to 2007
$784k
NHGRI NIH HHS HG001715NHGRI NIH HHS HG003224NHGRI NIH HHS HG004233NHGRI NIH HHS P50 HG004233NHGRI NIH HHS R01 HG001715NHGRI NIH HHS R01 HG003224NHGRI NIH HHS U01 HG001715NHGRI NIH HHS U41 HG001715NHLBI NIH HHS HL081341NHLBI NIH HHS U01 HL081341NINDS NIH HHS NS035611NINDS NIH HHS NS054052NINDS NIH HHS P01 NS035611NINDS NIH HHS R01 NS054052
6 · The paper itself

Abstract

summaryComputational gene function prediction can serve to focus experimental resources on high-priority experimental tasks. FuncBase is a web resource for viewing quantitative machine learning-based gene function annotations. Quantitative annotations of genes, including fungal and mammalian genes, with Gene Ontology terms are accompanied by a community feedback system. Evidence underlying function annotations is shown. For example, a custom Cytoscape viewer shows functional linkage graphs relevant to the gene or function of interest. FuncBase provides links to external resources, and may be accessed directly or via links from species-specific databases. AVAILABILITY: FuncBase as well as all underlying data and annotations are freely available via http://func.med.harvard.edu/

Indexed as

SoftwareComputational BiologyDatabases, FactualGenesInternetVocabulary, Controlled

Identifiers

PMID20495000
PMCPMC2894510

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.