ArticleEnvironmental health perspectives2010
Temporal and spatial patterns of ambient endotoxin concentrations in Fresno, California.
Article in Environmental health perspectives, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 52 citations in OpenAlex.
- Targeting transitioning lung monocytes/macrophages as treatment strategies in lung disease related to environmental exposures.Respiratory research · 2024Article
- Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.Frontiers in immunology · 2024Article
- The joint effect of ambient air pollution and agricultural pesticide exposures on lung function among children with asthma.Environmental research · 2020Article
- Insights into Livestock-Related Microbial Concentrations in Air at Residential Level in a Livestock Dense Area.Environmental science & technology · 2019Article
- Coarse particulate matter (PMScientific reports · 2018Article
- Spatial Variation of Endotoxin Concentrations Measured in Ambient PMEnvironmental health perspectives · 2018Article
- Field Studies Measuring the Aerosolization of Endotoxin During the Land Application of Class B Biosolids.Aerobiologia · 2017Article
- Association of IL-6 with PMWater, air, and soil pollution · 2017Article
- Health Outcomes of Exposure to Biological and Chemical Components of Inhalable and Respirable Particulate Matter.International journal of environmental research and public health · 2016Review
- Particulate matter, endotoxin, and worker respiratory health on large Californian dairies.Journal of occupational and environmental medicine · 2015Article
- Modulation of distinct asthmatic phenotypes in mice by dose-dependent inhalation of microbial products.Environmental health perspectives · 2014Article
- Bioaerosols from a food waste composting plant affect human airway epithelial cell remodeling genes.International journal of environmental research and public health · 2013Article
- Article
- Polycyclic aromatic hydrocarbon exposure and wheeze in a cohort of children with asthma in Fresno, CA.Journal of exposure science & environmental epidemiology · 2012Article
- In vitro toxicity of particulate matter (PM) collected at different sites in the Netherlands is associated with PM composition, size fraction and oxidative potential--the RAPTES project.Particle and fibre toxicology · 2011Article
- Personal endotoxin exposure in a panel study of school children with asthma.Environmental health : a global access science source · 2011Article
- Population intervention models to estimate ambient NO2 health effects in children with asthma.Journal of exposure science & environmental epidemiologyArticle
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundEndotoxins are found in indoor dust generated by human activity and pets, in soil, and adsorbed onto the surfaces of ambient combustion particles. Endotoxin concentrations have been associated with respiratory symptoms and the risk of atopy and asthma in children.
objectiveWe characterized the temporal and spatial variability of ambient endotoxin in Fresno/Clovis, California, located in California's Central Valley, to identify correlates and potential predictors of ambient endotoxin concentrations in a cohort of children with asthma [Fresno Asthmatic Children's Environment Study (FACES)].
methodsBetween May 2001 and October 2004, daily ambient endotoxin and air pollutants were collected at the central ambient monitoring site of the California Air Resources Board in Fresno and, for shorter time periods, at 10 schools and indoors and outdoors at 84 residences in the community. Analyses were restricted to May-October, the dry months during which endotoxin concentrations are highest.
resultsDaily endotoxin concentration patterns were determined mainly by meteorologic factors, particularly the degree of air stagnation. Overall concentrations were lowest in areas distant from agricultural activities. Highest concentrations were found in areas immediately downwind from agricultural/pasture land. Among three other measured air pollutants [fine particulate matter, elemental carbon (a marker of traffic in Fresno), and coarse particulate matter (PMc)], PMc was the only pollutant correlated with endotoxin. Endotoxin, however, was the most spatially variable.
conclusionsOur data support the need to evaluate the spatial/temporal variability of endotoxin concentrations, rather than relying on a few measurements made at one location, in studies of exposure and and respiratory health effects, particularly in children with asthma and other chronic respiratory diseases.
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