ReviewTrends in cell biology2010
Polarity and endocytosis: reciprocal regulation.
Review in Trends in cell biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed.
- Mitochondrial asymmetry shifts T cell fate.Nature cell biology · 2026Article
- Deacetylase SIRT2 Inhibition Promotes Microglial M2 Polarization Through Axl/PI3K/AKT to Alleviate White Matter Injury After Subarachnoid Hemorrhage.Translational stroke research · 2025Article
- Morphology and molecular phylogeny ofFrontiers in cellular and infection microbiology · 2025Article
- Para- and Transcellular Transport Kinetics of Nanoparticles across Lymphatic Endothelial Cells.Molecular pharmaceutics · 2024Article
- Adhesion and Polarity protein distribution-regulates hexagon dominated plasma membrane organization in Drosophila blastoderm embryos.Genetics · 2023Article
- The biosynthetic-secretory pathway, supplemented by recycling routes, determines epithelial membrane polarity.Science advances · 2023Article
- Endocytosis at the Crossroad of Polarity and Signaling Regulation: Learning fromInternational journal of molecular sciences · 2022Review
- Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity.Molecules and cells · 2021Article
- Review
- Ubiquitous macropinocytosis in anthozoans.eLife · 2020Article
- Class III PI3K Vps34 Controls Thyroid Hormone Production by Regulating Thyroglobulin Iodination, Lysosomal Proteolysis, and Tissue Homeostasis.Thyroid : official journal of the American Thyroid Association · 2020Article
- Autophagy and Tumorigenesis in Drosophila.Advances in experimental medicine and biology · 2019Review
- Modeling Tissue Polarity in Context.Journal of molecular biology · 2018Review
- Papillomaviruses and Endocytic Trafficking.International journal of molecular sciences · 2018Review
- Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis.Nature communications · 2018Article
- The REN4 rheostat dynamically coordinates the apical and lateral domains of Arabidopsis pollen tubes.Nature communications · 2018Article
- WAVE regulates Cadherin junction assembly and turnover during epithelial polarization.Developmental biology · 2018Article
- A dual role of the extracellular domain ofBiology open · 2018Article
- High MYC Levels Favour Multifocal Carcinogenesis.Frontiers in genetics · 2018Article
- EPEC effector EspF promotes Crumbs3 endocytosis and disrupts epithelial cell polarity.Cellular microbiology · 2017Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The establishment and maintenance of polarized plasma membrane domains is essential for cellular function and proper development of organisms. The molecules and pathways involved in determining cell polarity are remarkably well conserved between animal species. Historically, exocytic mechanisms have received primary emphasis among trafficking routes responsible for cell polarization. Accumulating evidence now reveals that endocytosis plays an equally important role in the proper localization of key polarity proteins. Intriguingly, some polarity proteins can also regulate the endocytic machinery. Here, we review emerging evidence for the reciprocal regulation between polarity proteins and endocytic pathways, and discuss possible models for how these distinct processes could interact to create separate cellular domains.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.