ReviewSeminars in thrombosis and hemostasis2010
Heterogeneity and plasticity of lymphatic endothelial cells.
Review in Seminars in thrombosis and hemostasis, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Single-cell transcriptomic profiling reveals distinct tumor microenvironments in HPV-associated penile squamous cell carcinoma.Precision clinical medicine · 2025Article
- Analysis of extracellular vesicle microRNA profiles reveals distinct blood and lymphatic endothelial cell origins.Journal of extracellular biology · 2024Article
- Synthetic hyaluronic acid coating preserves the phenotypes of lymphatic endothelial cells.Biomaterials science · 2023Article
- PROX1, a Key Mediator of the Anti-Proliferative Effect of Rapamycin on Hepatocellular Carcinoma Cells.Cells · 2022Article
- A short review on lymphatic endothelial cell heterogeneity.Inflammation and regeneration · 2021Review
- Neuroinflammation-Driven Lymphangiogenesis in CNS Diseases.Frontiers in cellular neuroscience · 2021Review
- Diversity of Organism-Wide and Organ-Specific Endothelial Cells.Current cardiology reports · 2020Review
- A Dual Targeting Magnetic Nanoparticle for Human Cancer Detection.Nanoscale research letters · 2019Article
- Heterogeneity of tumor lymphangiogenesis: Progress and prospects.Cancer science · 2018Review
- Endothelial Progenitor Cells for the Vascularization of Engineered Tissues.Tissue engineering. Part B, Reviews · 2018Review
- Cellular and Molecular Heterogeneity Associated with Vessel Formation Processes.BioMed research international · 2018Review
- Article
- The Hepatic Lymphatic Vascular System: Structure, Function, Markers, and Lymphangiogenesis.Cellular and molecular gastroenterology and hepatology · 2016Review
- Rapamycin up-regulates triglycerides in hepatocytes by down-regulating Prox1.Lipids in health and disease · 2016Article
- HIF-1α expression correlates with cellular apoptosis, angiogenesis and clinical prognosis in rectal carcinoma.Pathology oncology research : POR · 2014Article
- Regulation of T-cell Tolerance by Lymphatic Endothelial Cells.Journal of clinical & cellular immunology · 2014Article
- Article
- Article
- Initial afferent lymphatic vessels controlling outbound leukocyte traffic from skin to lymph nodes.Frontiers in immunology · 2013Review
- Lymphatic reprogramming by Kaposi sarcoma herpes virus promotes the oncogenic activity of the virus-encoded G-protein-coupled receptor.Cancer research · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Endothelial cells are found in most organs and tissues in our body. Despite their apparent morphological and functional similarities, endothelial cells exhibit remarkable heterogeneity and plasticity. In a strict sense, no two endothelial cells are identical in terms of their biological, immunological, functional, metabolic, morphological, and anatomical aspects. Their heterogeneity and plasticity are now known to be dependent upon and conferred by their microenvironments, arteriovenous-lymphatic cell identity, organ-specific vascular beds, fluid dynamics, vessel sizes, anatomical locations, physiological and pathological states, and more. Although abundant evidence is available to demonstrate endothelial heterogeneity in the blood vascular system, studies of heterogeneity and plasticity of lymphatic endothelial cells are limited because of the short history of lymphatic research. Nonetheless, a growing body of exciting work has begun to discover that lymphatic endothelial cells are as heterogeneous as blood vascular endothelial cells. In this article, we discuss the heterogeneity and plasticity of lymphatic endothelial cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.