Evidence map›Paper›PMID 20490485›Full record

ArticlePediatric radiology2010

Incidental thyroid abnormalities identified on neck US for non-thyroid disorders.

Shivaram Avula, Alan Daneman, Oscar M Navarro, Rahim Moineddin, Stacey Urbach, Denis Daneman

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Article in Pediatric radiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 65 citations in OpenAlex.

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  17. Observational
  18. Thyroid disease in children and adolescents.Ultrasonography (Seoul, Korea) · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Shivaram AvulaDepartment of Diagnostic Imaging, The Hospital for Sick Children and University of Toronto, 555 University Ave., Toronto, ON M5G 1X8, Canada.
Alan Daneman
Oscar M Navarro
Rahim Moineddin
Stacey Urbach
Denis Daneman
Hospital for Sick Children · CAPublic Health Ontario · CASickKids Foundation · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncidental thyroid abnormalities detected on US examinations in children have not been well documented.

objectiveTo determine prevalence of incidental thyroid abnormalities depicted by US in children and to describe the spectrum of appearances. MATERIALS AND

methodsRetrospective analysis of clinical and US findings in children who had neck US from January 2006 to December 2007.

resultsOf 1,228 neck US exams, thyroid was depicted in 287 children (mean age = 6.2 years). Incidental thyroid abnormalities were detected in 52 (18%) (mean age = 8.1 years). In 35 there were small (<4 mm), well-defined cysts, some with a hyperechoic punctate focus. In nine there were hypoechoic, solid nodules with smooth, straighter margins with echogenicity similar to thymus, suggesting intrathyroid ectopic thymus (mean age = 2.5 years). In three others there were tiny hyperechoic foci without nodules. Other abnormalities included hypoechoic target-like lesions (n = 2), isoechoic nodule (n = 1), multiple hypoechoic foci (n = 1) and non-visualized thyroid lobe resulting from adjacent abscess (n = 1). None of the children developed thyroid dysfunction or malignancy.

conclusionThere is a spectrum of incidental thyroid abnormalities in children. These US findings should be interpreted cautiously, avoiding unnecessary referrals and investigations. Intrathyroid ectopic thymus is more common than previously thought, occurs much more frequently in younger boys and should be considered if the lesion has US characteristics of thymus.

Indexed as

ChildFemaleHumansIncidental FindingsMaleNeckOntarioPrevalenceRisk AssessmentRisk FactorsSex DistributionThyroid DiseasesUltrasonography

Identifiers

PMID20490485
OpenAlexW2052581827

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.