Evidence map›Paper›PMID 20490314›Full record

ArticleJournal of clinical biochemistry and nutrition2010

Progression from chronic atrophic gastritis to gastric cancer; tangle, toggle, tackle with Korea red ginseng.

Yoon Jae Kim, Jun Won Chung, So Jung Lee, Ki Seok Choi, Ju Hyun Kim, Ki Baik Hahm

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical biochemistry and nutrition, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Effect of acacetin on inhibition of apoptosis inWorld journal of gastrointestinal oncology · 2024
    Article
  3. Article
  4. Curcumol Undermines SDF-1Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  5. Rejuvenation ofFrontiers in pharmacology · 2021
    Article
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  7. Review
  8. Review
  9. Article
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  11. Article
  12. Review
  13. Article
  14. Article
  15. Gastric cancer - histopathological correlations between tumor and non-tumor gastric mucosa changes.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yoon Jae KimDepartment of Gastroenterology Gachon Graduate School of Medicine, 7-45 Songdo-dong, Yeonsu-gu, Incheon 406-840, Korea.
Jun Won Chung
So Jung Lee
Ki Seok Choi
Ju Hyun Kim
Ki Baik Hahm
Gachon University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Key molecular players that link inflammation to carcinogenesis are prostaglandins, cytokines, nuclear factor-kappaB (NF-kappaB), chemokines, angiogenic growth factors, and free radicals, all of which lead to increased mutations and altered functions of important enzymes and proteins, for example, activation of oncogenic products and/or inhibition of tumor suppressor proteins, in inflamed tissues, thus contributing to multi-stage carcinogenesis process. Interpreted reversely, the identification of the molecular mechanisms by which chronic inflammation increases cancer risk or optimal intervention of targeted drugs or agents during the inflammation-associated carcinogenic process could be a necessary basis for developing new strategy of cancer prevention at many sites. In this review, we discuss the possibilities for cancer prevention by controlling inflammation process in Helicobacter pylori (H. pylori)-associated inflamed stomach with Korea red ginseng. Korea red ginseng is a good example of a natural herb that has ubiquitous properties that are conductive to stop inflammatory carcinogenesis that is un wanted outcome of H. pylori infection, rendering rejuvenation of chronic atrophic gastritis.

Indexed as

cancer preventioncarcinogenesisinflammationKorea red ginsengrejuvenation

Identifiers

PMID20490314
PMCPMC2872224
OpenAlexW2006114566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.