ArticleThe Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation2010
Speckle-tracking 2-dimensional strain echocardiography: a new noninvasive imaging tool to evaluate acute rejection in cardiac transplantation.
Article in The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 47 citations in OpenAlex.
- Changes in circumferential strain can differentiate pediatric heart transplant recipients with and without graft rejection.Pediatric transplantation · 2022Article
- Non-invasive cardiac allograft rejection surveillance: reliability and clinical value for prevention of heart failure.Heart failure reviews · 2021Review
- Favorable changes of left ventricular function in the circumferential direction following transcatheter atrial septal defect closure: a strain imaging study.The international journal of cardiovascular imaging · 2021Article
- Tissue Doppler velocities for ruling out rejection in heart transplant recipients in the context of myocardial strain imaging: a multivariate, prospective, single-center study.The international journal of cardiovascular imaging · 2020Article
- Diastolic strain imaging: a new non-invasive tool to detect subclinical myocardial dysfunction in early cardiac allograft rejection.The international journal of cardiovascular imaging · 2020Article
- Position Statement on Indications of Echocardiography in Adults - 2019.Arquivos brasileiros de cardiologia · 2019Article
- Temporal changes in left ventricular strain with the development of rejection in paediatric heart transplant recipients.Cardiology in the young · 2019Article
- Use of speckle-tracking echocardiography-derived strain and systolic strain rate measurements to predict rejection in transplant hearts with preserved ejection fraction.BMC cardiovascular disorders · 2018Article
- Echocardiographic assessment of myocardial infarction: comparison of a rat model in two strains.Iranian journal of veterinary research · 2017Article
- Strain Imaging Echocardiography: What Imaging Cardiologists Should Know.Current cardiology reviews · 2017Article
- Cardiac mechanics in heart transplant recipients with and without transplant vasculopathy.The international journal of cardiovascular imaging · 2015Article
- Speckle tracking echocardiography detects uremic cardiomyopathy early and predicts cardiovascular mortality in ESRD.Journal of the American Society of Nephrology : JASN · 2014Article
- Increased regional deformation of the left ventricle in normal children with increased body mass index: implications for future cardiovascular health.Pediatric cardiology · 2014Article
- Cardiac injury after 10 gy total body irradiation: indirect role of effects on abdominal organs.Radiation research · 2013Article
- Advanced echocardiographic imaging of the congenitally malformed heart.Current cardiology reviews · 2013Review
- The natural history of biopsy-negative rejection after heart transplantation.Journal of transplantation · 2013Article
- Mitochondrial DNA variant for complex I reveals a role in diabetic cardiac remodeling.The Journal of biological chemistry · 2012Article
- Left atrial reservoir function predicts atrial fibrillation recurrence after catheter ablation: a two-dimensional speckle strain study.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2011Article
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6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThere remains no reliable non-invasive method to detect cardiac transplant rejection. Recently, speckle-tracking 2-dimensional strain echocardiography (2DSE) was shown to be sensitive in the early detection of myocardial dysfunction in various models of cardiomyopathy. We aim to determine if 2DSE-derived functional indices can detect cardiac transplant rejection.
methodsHeterotopic rat cardiac transplantation was performed in histocompatible isografts or histoincompatible allografts. Histologic rejection scores were determined. Short-axis, mid-left ventricular (LV) echocardiography was performed on Day 6 after transplantation. Conventional measures of function were measured, (including LV fractional shortening and ejection fraction) as well as 2DSE parameters.
resultsDespite class IIIB rejection in allografts and no rejection in isografts, there was no difference between isografts vs allografts in fractional shortening (15% +/- 3% vs 12% +/- 3%) or ejection fraction (36% +/- 5% vs 26% +/- 6%; both not significant). In contrast, 2DSE revealed decreases between isografts and allografts in global radial strain (12.6% +/- 5.6% vs 1.1% +/- 0.2%, p < 0.05), peak radial systolic strain rate (3.10 +/- 0.74/s vs 0.54 +/- 0.13/s, p < 0.001), and peak circumferential systolic strain rate (-1.99 +/- 0.55 vs -0.43 +/- 0.11/s; p < 0.01).
conclusionsSystolic strain imaging using 2DSE differentiates myocardial function between experimental cardiac transplant rejection in allografts and non-rejection in isografts. Therefore, 2DSE may be useful in early non-invasive detection of transplant rejection.
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