ArticleJournal of experimental & clinical assisted reproduction2009
Ovarian hyperstimulation syndrome: current views on pathophysiology, risk factors, prevention, and management.
Article in Journal of experimental & clinical assisted reproduction, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 75 citations in OpenAlex.
- A Woman's Infertility Journey Complicated by Severe Ovarian Hyperstimulation Syndrome - A Case Report.Journal of education & teaching in emergency medicine · 2026Article
- Multidisciplinary perioperative management in dilatation and evacuation for a giant hydatidiform mole: A case report.Case reports in women's health · 2023Article
- Female with peritonitis and abdominal distention.Journal of the American College of Emergency Physicians open · 2023Article
- A Narrative Review Discussing the Efficiency of Personalized Dosing Algorithm of Follitropin Delta for Ovarian Stimulation and the Reproductive and Clinical Outcomes.Diagnostics (Basel, Switzerland) · 2023Review
- Severe ovarian hyperstimulation syndrome requiring recurrent large-volume paracenteses until 21 weeks' gestation: a case report.F&S reports · 2022Article
- Polycystic Ovary Syndrome Develops the Complications of Assisted Reproductive Technologies.Archives of Razi Institute · 2022Article
- Nintedanib Treatment After Ovulation is an Effective Therapeutic Strategy for the Alleviation of Ovarian Hyperstimulation Syndrome (OHSS) in a Mouse Model.Drug design, development and therapy · 2022Article
- Effects of controlled ovarian stimulation on vascular barrier and endothelial glycocalyx: a pilot study.Journal of assisted reproduction and genetics · 2021Article
- Article
- Prognostic role of follicular fluid tumor necrosis factor alpha in the risk of early ovarian hyperstimulation syndrome.BMC pregnancy and childbirth · 2020Article
- The N680S variant in the follicle-stimulating hormone receptor gene identifies hyperresponders to controlled ovarian stimulation.Pharmacogenetics and genomics · 2019Article
- In-vitro fertilization resulting in heterotopic pregnancy, ovarian hyperstimulation and paralytic ileus: A case report.Case reports in women's health · 2019Article
- Ovarian Hyperstimulation Syndrome: A Narrative Review of Its Pathophysiology, Risk Factors, Prevention, Classification, and Management.Iranian journal of medical sciences · 2018Review
- Herbal Medicines and Ovarian Hyperstimulation Syndrome: A Retrospective Cohort Study.Obstetrics and gynecology international · 2016Article
- Prediction of Ovarian Hyperstimulation Syndrome in Patients Treated with Corifollitropin alfa or rFSH in a GnRH Antagonist Protocol.PloS one · 2016Article
- An IVF pregnancy, a neck lump and shortness of breath.Clinical medicine (London, England) · 2015Article
- Spontaneous Late Onset OHSS in Singleton Pregnancy in 2nd Trimester: A Rare Case.Journal of obstetrics and gynaecology of India · 2015Article
- Ovarian hyperstimulation syndrome, the master of disguise?Case reports in emergency medicine · 2015Article
- Predictive factors for recovery time in patients suffering from severe OHSS.Reproductive biology and endocrinology : RB&E · 2014Article
- A case of severe ovarian hyperstimulation syndrome.Indian journal of clinical biochemistry : IJCB · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo summarize current views on the pathophysiology, risk factors, prevention, clinical features, and management of Ovarian Hyperstimulation Syndrome (OHSS).
designLiterature review
resultsOHSS is a condition characterized by increased capillary permeability, and experimental evidence has identified a provocative link to pathologic vasoactive cytokine actions. Although the ultimate physiologic mechanism of OHSS is not yet known, there are well-known risk factors that must be considered during the administration of medications to treat infertility. Clinical features are consequences of third-spaced intravascular fluid, and OHSS may become life-threatening secondary to thromboembolism or compromised pulmonary or cardiovascular function. Cornerstones of prevention have historically included cycle cancellation, coasting, decreased dosing of human chorionic gonadotropin (hCG) trigger, use of an agonist trigger, and cryopreservation of all embryos. Newer methods of prevention include the administration of a dopamine agonist medication. Management options for OHSS include outpatient transvaginal paracentesis, outpatient transabdominal paracentesis, and inpatient hospitalization with or without paracentesis.
conclusionsOHSS continues to be a serious complication of assisted reproductive therapy (ART), with no universally agreed upon best method of prevention. Coasting and cryopreservation of all embryos are the most commonly used approaches in the literature, but cycle cancellation is the only method that can completely prevent the development of OHSS. Dopamine agonists are currently being investigated to both prevent and improve the clinical course in OHSS. Recent publications suggest that outpatient paracentesis both prevents the need for inpatient hospitalization and is a cost-effective strategy.
Indexed as
Identifiers
20485578PMC2868304W2167218982What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.