ArticlePloS one2010
Genetic epidemiology of attention deficit hyperactivity disorder (ADHD index) in adults.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 4 of them syntheses that pooled it.
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Who cites it
52 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- ADHD genetic burden associates with older epigenetic age: mediating roles of education, behavioral and sociodemographic factors among older adults.Clinical epigenetics · 2023Pooled it
- Association between MTHFR (677C>T and 1298A>C) polymorphisms and psychiatric disorder: A meta-analysis.PloS one · 2022Pooled it
- Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults.Biological psychiatry · 2019Pooled it
- Attention-deficit hyperactivity disorder in adults: A systematic review and meta-analysis of genetic, pharmacogenetic and biochemical studies.Molecular psychiatry · 2016Pooled it
- ADHD and Student Grades in Children from the ABCD StudyBehavior genetics · 2026Article
- Cell-Type-Specific WTAP and ALKBH5-Mediated mCNS neuroscience & therapeutics · 2026Article
- Using Bifactor Twin Modeling to Assess the Genetic and Environmental Dimensionality of Adult ADHD Symptoms.Behavior genetics · 2025Article
- Intergenerational transmission of genetic risk for hyperactivity and inattention. Direct genetic transmission or genetic nurture?JCPP advances · 2024Article
- Effortful Control Protects Against Familial Liability for ADHD: Longitudinal Results from the ABCD Study in the United States.Research on child and adolescent psychopathology · 2024Article
- The Challenges and Opportunities for Mental Health Twin Research in Nigeria.Behavior genetics · 2024Article
- Assortative mating and parental genetic relatedness contribute to the pathogenicity of variably expressive variants.American journal of human genetics · 2023Article
- Healthcare utilisation in the United Arab Emirates for children with attention-deficit hyperactivity disorder and comorbidities.BJPsych international · 2023Review
- Parental ADHD and ASD symptoms and contributions of psychosocial risk to childhood ADHD and ASD symptoms in children born very preterm.Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- Prenatal inflammation does not increase the risk for symptoms of attention deficit hyperactivity disorder (ADHD) in offspring.European child & adolescent psychiatry · 2021Article
- Identification of ADHD risk genes in extended pedigrees by combining linkage analysis and whole-exome sequencing.Molecular psychiatry · 2020Article
- Intergenerational Transmission of Education and ADHD: Effects of Parental Genotypes.Behavior genetics · 2020Article
- Using the tools of genetic epidemiology to understand sex differences in neuropsychiatric disorders.Genes, brain, and behavior · 2020Review
- The (Broad-Sense) Genetic Correlations Among Four Measures of Inattention and Hyperactivity in 12 Year Olds.Behavior genetics · 2020Article
- Development of the Korean Practice Parameter for Adult Attention-Deficit/Hyperactivity Disorder.Soa--ch'ongsonyon chongsin uihak = Journal of child & adolescent psychiatry · 2020Article
- In Quest of Pathognomonic/Endophenotypic Markers of Attention Deficit Hyperactivity Disorder (ADHD): Potential of EEG-Based Frequency Analysis and ERPs to Better Detect, Prevent and Manage ADHD.Medical devices (Auckland, N.Z.) · 2020Review
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextIn contrast to the large number of studies in children, there is little information on the contribution of genetic factors to Attention Deficit Hyperactivity Disorder (ADHD) in adults.
objectiveTo estimate the heritability of ADHD in adults as assessed by the ADHD index scored from the CAARS (Conners' Adult ADHD Rating Scales).
designPhenotype data from over 12,000 adults (twins, siblings and parents) registered with the Netherlands Twin Register were analyzed using genetic structural equation modeling.
main outcome measuresHeritability estimates for ADHD from the twin-family study.
resultsHeritability of ADHD in adults is estimated around 30% in men and women. There is some evidence for assortative mating. All familial transmission is explained by genetic inheritance, there is no support for the hypothesis that cultural transmission from parents to offspring is important.
conclusionHeritability for ADHD features in adults is present, but is substantially lower than it is in children.
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