Evidence map›Paper›PMID 20485473›Full record

ReviewFuture medicinal chemistry2010

Nanomedicine strategies for molecular targets with MRI and optical imaging.

Dipanjan Pan, Shelton D Caruthers, Junjie Chen, Patrick M Winter, Angana SenPan, Anne H Schmieder, Samuel A Wickline, Gregory M Lanza

Open access · greenAbstract readReview
In one paragraph

Review in Future medicinal chemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 89 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Perfluorocarbons-BasedInternational journal of nanomedicine · 2020
    Review
  10. Article
  11. Article
  12. Article
  13. White Paper on P4 Concepts for Pediatric Imaging.Journal of the American College of Radiology : JACR · 2016
    Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Transport of nanocarriers across gastrointestinal epithelial cells by a new transcellular route induced by targeting ICAM-1.Journal of controlled release : official journal of the Controlled Release Society · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Dipanjan Pan
Shelton D Caruthers
Junjie Chen
Patrick M Winter
Angana SenPan
Anne H Schmieder
Samuel A Wickline
Gregory M Lanza
Saint Louis University · US

Funding

UIUC Nanomaterials & Nanofabrication for Targeting CancerU54CA119342 · NCI · WASHINGTON UNIVERSITY · PI WICKLINE, SAMUEL A · 2005 to 2009
$16.5M
Task Specific Project 3: Diffuse Optical TomographyU54CA136398 · NCI · WASHINGTON UNIVERSITY · PI ACHILEFU, SAMUEL · 2008 to 2012
$6.0M
Fibrin-Specific Thrombolytic Nanoparticles for Acute StrokeR01NS059302 · NINDS · WASHINGTON UNIVERSITY · PI LANZA, GREGORY M · 2007 to 2011
$1.7M
Combined Therapeutic-Imaging Agent for AtherosclerosisR01HL078631 · NHLBI · WASHINGTON UNIVERSITY · PI LANZA, GREGORY M · 2004 to 2007
$1.5M
COLLOIDAL IRON-OXIDE NANOBEACONS FOR THERANOSTIC USE IN ATHEROSCLEROSISR01HL094470 · NHLBI · WASHINGTON UNIVERSITY · PI LANZA, GREGORY M · 2009 to 2010
$1.4M
Molecular Imaging of Angiogenesis by MRIR01EB001704 · NIBIB · WASHINGTON UNIVERSITY · PI LANZA, GREGORY M · 2004 to 2007
$946k
NCI NIH HHS U54 CA119342NCI NIH HHS U54 CA136398NHLBI NIH HHS R01 HL078631NHLBI NIH HHS R01 HL094470NIBIB NIH HHS R01 EB001704NINDS NIH HHS R01 NS059302
6 · The paper itself

Abstract

The science of 'theranostics' plays a crucial role in personalized medicine, which represents the future of patient management. Over the last decade an increasing research effort has focused on the development of nanoparticle-based molecular-imaging and drug-delivery approaches, emerging as a multidisciplinary field that shows promise in understanding the components, processes, dynamics and therapies of a disease at a molecular level. The potential of nanometer-sized agents for early detection, diagnosis and personalized treatment of diseases is extraordinary. They have found applications in almost all clinically relevant biomedical imaging modality. In this review, a number of these approaches will be presented with a particular emphasis on MRI and optical imaging-based techniques. We have discussed both established molecular-imaging approaches and recently developed innovative strategies, highlighting the seminal studies and a number of successful examples of theranostic nanomedicine, especially in the areas of cardiovascular and cancer therapy.

Indexed as

AnimalsDiagnostic ImagingDrug Delivery SystemsFerric CompoundsHumansMagnetic Resonance ImagingMagneticsMolecular StructureNanomedicineNanoparticlesPrecision MedicineQuantum DotsFerric Compoundsferric oxide

Identifiers

PMID20485473
PMCPMC2871711
OpenAlexW2072003201

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.