IRF-3 partners Bax in a viral-induced dance macabre.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

14 citing papers in PubMed.

1. PBLD promotes IRF3 mediated the type I interferon (IFN-I) response and apoptosis to inhibit viral replication.Cell death & disease · 2024
   Article
2. KDM5A/B contribute to HIV-1 latent infection and survival of HIV-1 infected cells.Antiviral research · 2024
   Article
3. Intravitreal injection of mitochondrial DNA induces cell damage and retinal dysfunction in rats.Biological research · 2022
   Article
4. Apoptosis during ZIKA Virus Infection: Too Soon or Too Late?International journal of molecular sciences · 2022
   Review
5. Poly (I:C)- and doxorubicin-loaded magnetic dendrimeric nanoparticles affect the apoptosis-related gene expressions in MCF-7 cells.Turkish journal of biology = Turk biyoloji dergisi · 2020
   Article
6. Frontiers in cellular and infection microbiology · 2016
   Article
7. Transfected poly(I:C) activates different dsRNA receptors, leading to apoptosis or immunoadjuvant response in androgen-independent prostate cancer cells.The Journal of biological chemistry · 2015
   Article
8. TLR3 engagement induces IRF-3-dependent apoptosis in androgen-sensitive prostate cancer cells and inhibits tumour growth in vivo.Journal of cellular and molecular medicine · 2015
   Article
9. RIG-I enhanced interferon independent apoptosis upon Junin virus infection.PloS one · 2014
   Article
10. The pestivirus N terminal protease N(pro) redistributes to mitochondria and peroxisomes suggesting new sites for regulation of IRF3 by N(pro.).PloS one · 2014
    Article
11. NDV-induced apoptosis in absence of Bax; evidence of involvement of apoptotic proteins upstream of mitochondria.Virology journal · 2012
    Article
12. IκB kinase ε-dependent phosphorylation and degradation of X-linked inhibitor of apoptosis sensitizes cells to virus-induced apoptosis.Journal of virology · 2012
    Article
13. Defective NF-κB signaling in metastatic head and neck cancer cells leads to enhanced apoptosis by double-stranded RNA.Cancer research · 2012
    Article
14. Function and regulation of retinoic acid-inducible gene-I.Critical reviews in immunology · 2010
    Review

Corrections and comments

• Comment on
  Viral apoptosis is induced by IRF-3-mediated activation of Bax.2010

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as