ArticleBMC genomics2010
The collapse of gene complement following whole genome duplication.
Article in BMC genomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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Who cites it
68 citing papers in PubMed, 131 citations in OpenAlex.
- A chromosome-level genome assembly of the varied leaved jewelflower, Streptanthus diversifolius, reveals a recent whole genome duplication.G3 (Bethesda, Md.) · 2025Article
- Insights from the first chromosome-level genome assembly of the alpine gentian Gentiana straminea Maxim.DNA research : an international journal for rapid publication of reports on genes and genomes · 2024Article
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- The Gynandropsis gynandra genome provides insights into whole-genome duplications and the evolution of C4 photosynthesis in Cleomaceae.The Plant cell · 2023Article
- Genome assembly of an Australian native grass species reveals a recent whole-genome duplication and biased gene retention of genes involved in stress response.GigaScience · 2022Article
- Conservation and Divergence of the Trihelix Genes in Brassica and Expression Profiles ofInternational journal of molecular sciences · 2022Article
- Article
- Genome-wide identification, expression analysis and evolutionary relationships of the IQ67-domain gene family in common wheat (Triticum aestivum L.) and its progenitors.BMC genomics · 2022Article
- Repeatome-Based Phylogenetics in Pelargonium Section Ciconium (Sweet) Harvey.Genome biology and evolution · 2021Article
- The pan-genome of the cultivated soybean (PanSoy) reveals an extraordinarily conserved gene content.Plant biotechnology journal · 2021Article
- An ancient whole-genome duplication event and its contribution to flavor compounds in the tea plant (Camellia sinensis).Horticulture research · 2021Article
- Genes Encoding Teleost Orthologs of Human Haploinsufficient and Monoallelically Expressed Genes Remain in Duplicate More Frequently Than the Whole Genome.International journal of genomics · 2021Article
- Evolution of PHAS loci in the young spike of Allohexaploid wheat.BMC genomics · 2020Article
- Article
- Excision Dominates Pseudogenization During Fractionation After Whole Genome Duplication and in Gene Loss After Speciation in Plants.Frontiers in genetics · 2020Article
- Genome-wide analysis of spatiotemporal gene expression patterns during floral organ development in Brassica rapa.Molecular genetics and genomics : MGG · 2019Article
- Eukaryote hybrid genomes.PLoS genetics · 2019Article
- Genes Encoding Teleost Fish Ligands and Associated Receptors Remained in Duplicate More Frequently than the Rest of the Genome.Genome biology and evolution · 2019Article
- Towards the new normal: Transcriptomic convergence and genomic legacy of the two subgenomes of an allopolyploid weed (Capsella bursa-pastoris).PLoS genetics · 2019Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGenome amplification through duplication or proliferation of transposable elements has its counterpart in genome reduction, by elimination of DNA or by gene inactivation. Whether loss is primarily due to excision of random length DNA fragments or the inactivation of one gene at a time is controversial. Reduction after whole genome duplication (WGD) represents an inexorable collapse in gene complement.
resultsWe compare fifteen genomes descending from six eukaryotic WGD events 20-450 Mya. We characterize the collapse over time through the distribution of runs of reduced paralog pairs in duplicated segments. Descendant genomes of the same WGD event behave as replicates. Choice of paralog pairs to be reduced is random except for some resistant regions of contiguous pairs. For those paralog pairs that are reduced, conserved copies tend to concentrate on one chromosome.
conclusionsBoth the contiguous regions of reduction-resistant pairs and the concentration of runs of single copy genes on a single chromosome are evidence of transcriptional co-regulation, dosage sensitivity or other functional interaction constraining the reduction process. These constraints and their evolution over time show a consistent pattern across evolutionary domains and a highly reproducible pattern, as replicates, for the several descendants of a single WGD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.