ArticleBMC bioinformatics2010
Screensaver: an open source lab information management system (LIMS) for high throughput screening facilities.
Article in BMC bioinformatics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Identification of novel small molecule inhibitors of twin arginine translocation (Tat) pathway and their effect on the control ofFrontiers in microbiology · 2024Article
- RNA Interference (RNAi) Screening inGenetics · 2018Article
- PubChem BioAssay: A Decade's Development toward Open High-Throughput Screening Data Sharing.SLAS discovery : advancing life sciences R & D · 2017Article
- Comprehensive analysis of high-throughput screens with HiTSeekR.Nucleic acids research · 2016Article
- VAV3 mediates resistance to breast cancer endocrine therapy.Breast cancer research : BCR · 2014Article
- Biomarkers in autism spectrum disorder: the old and the new.Psychopharmacology · 2014Review
- ScreenSifter: analysis and visualization of RNAi screening data.BMC bioinformatics · 2013Article
- siRNA Genome Screening Approaches to Therapeutic Drug Repositioning.Pharmaceuticals (Basel, Switzerland) · 2013Article
- Regulation of zebrafish sleep and arousal states: current and prospective approaches.Frontiers in neural circuits · 2013Review
- LAS: a software platform to support oncological data management.Journal of medical systems · 2012Article
- MScreen: an integrated compound management and high-throughput screening data storage and analysis system.Journal of biomolecular screening · 2012Article
- Transforming microbial genotyping: a robotic pipeline for genotyping bacterial strains.PloS one · 2012Article
- A case study for efficient management of high throughput primary lab data.BMC research notes · 2011Article
- Brunn: an open source laboratory information system for microplates with a graphical plate layout design process.BMC bioinformatics · 2011Article
- Traditional Medicine Collection Tracking System (TM-CTS): a database for ethnobotanically driven drug-discovery programs.Journal of ethnopharmacology · 2011Article
- LabKey Server: an open source platform for scientific data integration, analysis and collaboration.BMC bioinformatics · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
backgroundShared-usage high throughput screening (HTS) facilities are becoming more common in academe as large-scale small molecule and genome-scale RNAi screening strategies are adopted for basic research purposes. These shared facilities require a unique informatics infrastructure that must not only provide access to and analysis of screening data, but must also manage the administrative and technical challenges associated with conducting numerous, interleaved screening efforts run by multiple independent research groups.
resultsWe have developed Screensaver, a free, open source, web-based lab information management system (LIMS), to address the informatics needs of our small molecule and RNAi screening facility. Screensaver supports the storage and comparison of screening data sets, as well as the management of information about screens, screeners, libraries, and laboratory work requests. To our knowledge, Screensaver is one of the first applications to support the storage and analysis of data from both genome-scale RNAi screening projects and small molecule screening projects.
conclusionsThe informatics and administrative needs of an HTS facility may be best managed by a single, integrated, web-accessible application such as Screensaver. Screensaver has proven useful in meeting the requirements of the ICCB-Longwood/NSRB Screening Facility at Harvard Medical School, and has provided similar benefits to other HTS facilities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.