ReviewEuropean journal of applied physiology2010
Evidence for sex differences in cardiovascular aging and adaptive responses to physical activity.
Review in European journal of applied physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 2 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Publication guidelines for human heart rate and heart rate variability studies in psychophysiology-Part 1: Physiological underpinnings and foundations of measurement.Psychophysiology · 2024Guideline
- Cardiorespiratory Fitness in Severe Mental Illness: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2017Pooled it
- A single dose of dietary nitrate supplementation protects against endothelial ischemia-reperfusion injury in early postmenopausal women.Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 2022Trial
- Low-volume cycling training improves body composition and functionality in older people with multimorbidity: a randomized controlled trial.Scientific reports · 2021Trial
- Cardiac Adaptations to High-Intensity Aerobic Training in Premenopausal and Recent Postmenopausal Women: The Copenhagen Women Study.Journal of the American Heart Association · 2017Trial
- Essential role of estrogen for improvements in vascular endothelial function with endurance exercise in postmenopausal women.The Journal of clinical endocrinology and metabolism · 2013Trial
- Does the mode of exercise influence recovery of functional capacity in the early postoperative period after coronary artery bypass graft surgery? A randomized controlled trial.Interactive cardiovascular and thoracic surgery · 2012Trial
- Sex-specific effect of aging on submaximal leg exercise hemodynamics in middle-aged and older adults.European journal of applied physiology · 2011Trial
- Sex-specific effects of habitual aerobic exercise on brachial artery flow-mediated dilation in middle-aged and older adults.Clinical science (London, England : 1979) · 2011Trial
- Trial
- Article
- Midlife aging and performance study (MAPS): evaluating biological aging through a physical capacity battery.GeroScience · 2026Article
- Sex-specific molecular drivers of cardiac fibrosis in aging hearts.GeroScience · 2025Article
- Biological Sex and the Association Between Grip Strength and Cardiovascular Disease: a Scoping Review.Canadian geriatrics journal : CGJ · 2025Review
- Sex-Specific Patterns in Blood Pressure and Vascular Parameters: The MUJER-EVA Project.Journal of cardiovascular development and disease · 2025Article
- Effect of Prior Moderate Aerobic Exercise to Prolonged Sitting on Peripheral and Central Cardiovascular Measures in Young Women.Journal of cardiovascular development and disease · 2024Article
- Metabolic equivalents intensity thresholds for physical activity classification in older adults.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2024Article
- Effects of aging and endurance exercise training on cardiorespiratory fitness and cardiac structure and function in healthy midlife and older women.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Review
- Physical activity during early life and the risk of all-cause mortality in midlife: findings from a birth cohort study.European journal of public health · 2023Article
- Neighbourhood greenness moderates the association between physical activity and geriatric-relevant health outcomes: an analysis of the CLSA.BMC geriatrics · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
There are considerable data addressing sex-related differences in cardiovascular system aging and disease risk/progression. Sex differences in cardiovascular aging are evident during resting conditions, exercise, and other acute physiological challenges (e.g., orthostasis). In conjunction with these sex-related differences-or perhaps even as an underlying cause-the impact of cardiorespiratory fitness and/or physical activity on the aging cardiovascular system also appears to be sex-specific. Potential mechanisms contributing to sex-related differences in cardiovascular aging and adaptability include changes in sex hormones with age as well as sex differences in baseline fitness and the dose of activity needed to elicit cardiovascular adaptations. The purpose of the present paper is thus to review the primary research regarding sex-specific plasticity of the cardiovascular system to fitness and physical activity in older adults. Specifically, the paper will (1) briefly review known sex differences in cardiovascular aging, (2) detail emerging evidence regarding observed cardiovascular outcomes in investigations of exercise and physical activity in older men versus women, (3) explore mechanisms underlying the differing adaptations to exercise and habitual activity in men versus women, and (4) discuss implications of these findings with respect to chronic disease risk and exercise prescription.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.