Evidence map›Paper›PMID 20480022›Full record

ReviewInternational journal of molecular sciences2010

Bioavailability of the polyphenols: status and controversies.

Massimo D'Archivio, Carmelina Filesi, Rosaria Varì, Beatrice Scazzocchio, Roberta Masella

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 302 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
302citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

302 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Biological Mechanisms of Polyphenols againstInfectious disorders drug targets · 2025
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  15. Liposomal Delivery ofPharmaceutics · 2026
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242 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Massimo D'ArchivioDepartment of Veterinary Public Health and Food Safety, Italian National Institute of Health, Rome, Italy. maxdar@iss.it <maxdar@iss.it>
Carmelina Filesi
Rosaria Varì
Beatrice Scazzocchio
Roberta Masella

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current interest in polyphenols has been driven primarily by epidemiological studies. However, to establish conclusive evidence for the effectiveness of dietary polyphenols in disease prevention, it is useful to better define the bioavailability of the polyphenols, so that their biological activity can be evaluated. The bioavailability appears to differ greatly among the various phenolic compounds, and the most abundant ones in our diet are not necessarily those that have the best bioavailability profile. In the present review, we focus on the factors influencing the bioavailability of the polyphenols. Moreover, a critical overview on the difficulties and the controversies of the studies on the bioavailability is discussed.

Indexed as

Biological AvailabilityDietFood AnalysisHumansIntestinal AbsorptionPolyphenolsPolyphenolsbioavailabilitydietary polyphenolsmetabolites

Identifiers

PMID20480022
PMCPMC2871118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.