ReviewMarine drugs2010
Biosynthesis and molecular genetics of polyketides in marine dinoflagellates.
Review in Marine drugs, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 127 citations in OpenAlex.
- Molecular Insights into Nutrient-Driven Regulation of Trophic Strategies and Life-Cycle Shifts in Bloom-Forming Mixotrophic Dinoflagellates.International journal of molecular sciences · 2026Review
- Transcriptomic insights into polyketides and toxin biosynthesis genes in freshwater dinoflagellates.Scientific reports · 2026Article
- Bioactive Polyketides fromMarine drugs · 2025Review
- Review
- Article
- Cyanotoxins, biosynthetic gene clusters, and factors modulating cyanotoxin biosynthesis.World journal of microbiology & biotechnology · 2023Review
- Article
- Transcription of biochemical defenses by the harmful brown tide pelagophyte,Frontiers in microbiology · 2023Article
- Vitamin BFundamental research · 2022Article
- Natural Polyether Ionophores and Their Pharmacological Profile.Marine drugs · 2022Review
- Alzheimer's Disease and Toxins Produced by Marine Dinoflagellates: An Issue to Explore.Marine drugs · 2022Review
- Review
- Antibacterial Activity and Amphidinol Profiling of the Marine DinoflagellateInternational journal of molecular sciences · 2021Article
- Unlocking the Health Potential of Microalgae as Sustainable Sources of Bioactive Compounds.International journal of molecular sciences · 2021Review
- From theFrontiers in microbiology · 2021Article
- A Polyol-Polyol Super-Carbon-Chain Compound Containing Thirty-Six Carbon Stereocenters from the DinoflagellateMarine drugs · 2020Article
- Integrated omics unveil the secondary metabolic landscape of a basal dinoflagellate.BMC biology · 2020Article
- Identification of Polyunsaturated Fatty Acids Synthesis Pathways in the Toxic DinophyteBiomolecules · 2020Article
- De novo Transcriptome of the Non-saxitoxin ProducingMarine drugs · 2020Article
- Mining Natural Product Biosynthesis in Eukaryotic Algae.Marine drugs · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Marine dinoflagellates are the single most important group of algae that produce toxins, which have a global impact on human activities. The toxins are chemically diverse, and include macrolides, cyclic polyethers, spirolides and purine alkaloids. Whereas there is a multitude of studies describing the pharmacology of these toxins, there is limited or no knowledge regarding the biochemistry and molecular genetics involved in their biosynthesis. Recently, however, exciting advances have been made. Expressed sequence tag sequencing studies have revealed important insights into the transcriptomes of dinoflagellates, whereas other studies have implicated polyketide synthase genes in the biosynthesis of cyclic polyether toxins, and the molecular genetic basis for the biosynthesis of paralytic shellfish toxins has been elucidated in cyanobacteria. This review summarises the recent progress that has been made regarding the unusual genomes of dinoflagellates, the biosynthesis and molecular genetics of dinoflagellate toxins. In addition, the evolution of these metabolic pathways will be discussed, and an outlook for future research and possible applications is provided.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.