ArticleVascular health and risk management2010
Mortality following operations for lower extremity peripheral arterial disease.
Article in Vascular health and risk management, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Percutaneous mechanical atherothrombectomy versus arterial bypass surgery for femoropopliteal in-stent restenosis: a budget impact analysis.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Asia-Pacific Consensus Statement on the Management of Peripheral Artery Disease: A Report from the Asian Pacific Society of Atherosclerosis and Vascular Disease Asia-Pacific Peripheral Artery Disease Consensus Statement Project Committee.Journal of atherosclerosis and thrombosis · 2020Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe sought to identify risk factors associated with mortality following surgery for peripheral arterial disease (PAD).
methodsWe evaluated the association between levels of control of atherosclerotic risk factors and time to mortality following either lower extremity bypass surgery or lower extremity amputation using Cox proportional hazards regression.
resultsAmong 796 patients with PAD (defined by an ankle-brachial index [ABI] < 0.9), 230 (28.9%) underwent an operation for PAD (136, lower-extremity bypasses; 111, lower-extremity amputations). Participants were followed for up to six years after their diagnosis of PAD. A total of 107 (46.5% of the 230) died during the period of follow-up. Factors associated with mortality following lower extremity bypass surgery included age 70 years and older hazard ratio [HR] 1.88; 95% confidence interval [CI]: 1.01-3.51) and of African American race (HR 1.94; 95% CI: 1.04-3.62). Renal insufficiency was significantly associated with mortality following lower extremity amputation (HR 2.19; 95% CI: 1.16-4.13).
conclusionOur data provide information on preoperative risk variables to consider when assessing long-term mortality in persons with PAD who are undergoing surgery for PAD.
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