ArticlePloS one2010
Fish consumption and omega-3 polyunsaturated fatty acids in relation to depressive episodes: a cross-sectional analysis.
Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Fish Consumption and the Risk of Depression: A Systematic Review and Meta-Analysis of Observational Studies.Nutrients · 2025Pooled it
- A Double-Blind Placebo-Controlled Trial of Omega-3 Fatty Acids as a Monotherapy for Adolescent Depression.The Journal of clinical psychiatry · 2018Trial
- Association between omega-6 and omega-3 fatty acids intake, body mass index and depression in young Iranian adults: a cross sectional study.Journal of health, population, and nutrition · 2026Article
- Relationship between food group-specific intake and depression among local government employees in Japan.BMC nutrition · 2024Article
- A Revision on the Effectiveness of Omega-3 Polyunsaturated Fatty Acids as Monotherapy in the Treatment of Major Depressive Disorder.International journal of clinical practice · 2022Review
- Disentangling the Molecular Mechanisms of the Antidepressant Activity of Omega-3 Polyunsaturated Fatty Acid: A Comprehensive Review of the Literature.International journal of molecular sciences · 2021Review
- Fish consumption and depression in Korean adults: the Korea National Health and Nutrition Examination Survey, 2013-2015.European journal of clinical nutrition · 2018Article
- Associations between Proportion of Plasma Phospholipid Fatty Acids, Depressive Symptoms and Major Depressive Disorder. Cross-Sectional Analyses from the AGES Reykjavik Study.The journal of nutrition, health & aging · 2018Article
- Sex Differences in the Relationship between Sleep Behavior, Fish Consumption, and Depressive Symptoms in the General Population of South Korea.International journal of environmental research and public health · 2017Article
- Altered serum fatty acid composition in geriatric depression.Journal of neural transmission (Vienna, Austria : 1996) · 2017Article
- Associations between omega fatty acid consumption and depressive symptoms among individuals seeking behavioural weight loss treatment.Obesity science & practice · 2016Article
- Associations of the Ratios of n-3 to n-6 Dietary Fatty Acids With Longitudinal Changes in Depressive Symptoms Among US Women.American journal of epidemiology · 2015Article
- Omega-3 fatty acid biomarkers and subsequent depressive symptoms.International journal of geriatric psychiatry · 2014Article
- Omega-3 and omega-6 content of medicinal foods for depressed patients: implications from the Iranian Traditional Medicine.Avicenna journal of phytomedicine · 2014Review
- Food-based strategies for depression management from Iranian traditional medicine resources.Iranian Red Crescent medical journal · 2014Article
- Omega-3 fatty acids and depression: scientific evidence and biological mechanisms.Oxidative medicine and cellular longevity · 2014Review
- Dietary treatment options for depression among diabetic patient, focusing on macronutrients.Journal of diabetes research · 2013Review
- N-3 (omega-3) Fatty acids in postpartum depression: implications for prevention and treatment.Depression research and treatment · 2011Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High fish consumption and omega-3 polyunsaturated fatty acid (PUFA) intake are suggested to benefit mental well-being but the current evidence is conflicting. Our aim was to evaluate whether a higher level of fish consumption, a higher intake of omega-3 PUFAs, and a higher serum concentration of omega-3 PUFAs link to a lower 12-month prevalence of depressive episodes.We used data from the nationwide Health 2000 Survey (n = 5492) and the Fishermen Study on Finnish professional fishermen and their family members (n = 1265). Data were based on questionnaires, interviews, health examinations, and blood samples. Depressive episodes were assessed with the M-CIDI (the Munich version of the Composite International Diagnostic Interview) and a self-report of two CIDI probe questions, respectively. Fish consumption was measured by a food frequency questionnaire (g/day) and independent frequency questions (times/month). Dietary intake (g/day) and serum concentrations (% from fatty acids) of PUFAs were determined. Fish consumption was associated with prevalence of depressive episodes in men but not in women. The prevalence of depressive episodes decreased from 9% to 5% across the quartiles of fish consumption (g/day) in men of the Health 2000 Survey (p for linear trend = 0.01), and from17% to 3% across the quartiles of fish consumption (times/month) in men of the Fishermen Study (p for linear trend = 0.05). This association was modified by lifestyle; in the Health 2000 Survey a higher level of fish consumption was related to a lower prevalence of depressive episodes in men who consumed the most alcohol, were occasional or former smokers, or had intermediate physical activity. The associations between depressive episodes and the intake or serum concentrations of omega-3 PUFAs were not consistent.In men, fish consumption appears as a surrogate for underlying but unidentified lifestyle factors that protect against depression.
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