Trial reportThe New England journal of medicine2010
Retropubic versus transobturator midurethral slings for stress incontinence.
Trial report in The New England journal of medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 6 registered trials, which are not on this map. Cited by 220 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
TOMUS-Trial Of Mid-Urethral Slings
Abdominal Colpopexy: Comparison of Endoscopic Surgical Strategies
The Effect of Mid-urethral Sling on the Urethral Dynamic Shape and Motion
Mesh-free Suture Urethropexy for Treating Stress Urinary Incontinence, Efficacy and Durability Trial
A Randomized Controlled Trial Comparing Retropubic KIM Sling to TVT Exact Midurethral Sling
Mesh-Reduced Sling For Treating Stress Urinary Incontinence, Efficacy and Durability Trial
Who cites it
220 citing papers in PubMed, 8 syntheses or guidelines pooled it, 685 citations in OpenAlex.
- Does Pre-Operative Grade of Stress Urinary Incontinence Severity Affect the Post-Operative Outcome? A Systematic Review.International urogynecology journal · 2025Pooled it
- Outcomes of concomitant midurethral sling and anterior colporrhaphy in managing stress urinary incontinence associated with cystocele: a systematic review and single-arm analysis.World journal of urology · 2025Pooled it
- How Do Surgical Interventions for Neurogenic Lower Urinary Tract Dysfunction Impact Quality of Life?Neurourology and urodynamics · 2025Pooled it
- Surgical Treatment for Stress Urinary Incontinence in Women: A Systematic Review and Meta-analysis.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2018Pooled it
- Mid-urethral sling operations for stress urinary incontinence in women.The Cochrane database of systematic reviews · 2017Pooled it
- Retropubic or transobturator mid-urethral slings for intrinsic sphincter deficiency-related stress urinary incontinence in women: a systematic review and meta-analysis.International urogynecology journal · 2016Pooled it
- Non-compliance with randomised allocation and missing outcome data in randomised controlled trials evaluating surgical interventions: a systematic review.BMC research notes · 2015Pooled it
- Effectiveness of midurethral slings in mixed urinary incontinence: a systematic review and meta-analysis.International urogynecology journal · 2011Pooled it
- Mini or Retropubic Sling in Women with Intrinsic Sphincter Deficiency at 12 Months-A Randomized Controlled Trial (Mini RISD).International urogynecology journal · 2026Trial
- Activity Restrictions After Midurethral Sling: A Randomized Controlled Trial.Urogynecology (Philadelphia, Pa.) · 2026Trial
- Return to work and normal activities after mid-urethral sling: secondary analysis of the Trial of Mid-Urethral Slings.International urogynecology journal · 2023Trial
- Long-term results of a prospective randomized trial comparing tension-free vaginal tape versus transobturator tape in stress urinary incontinence.International urogynecology journal · 2023Trial
- Single-incision mini-slings versus standard synthetic mid-urethral slings for surgical treatment of stress urinary incontinence in women: The SIMS RCT.Health technology assessment (Winchester, England) · 2022Trial
- Electroacupuncture for stress-related urinary incontinence in elderly women: data analysis from two randomised controlled studies.BMJ supportive & palliative care · 2022Trial
- Community-based Versus Traditional Research Among Older Minority Women With Urinary Incontinence.Female pelvic medicine & reconstructive surgery · 2022Trial
- Telemedicine follow-up is safe and efficacious for synthetic midurethral slings: a randomized, multi-institutional control trial.International urogynecology journal · 2022Trial
- Polypropylene and polyvinylidene fluoride transobturator slings for the treatment of female stress urinary incontinence: 1-Year outcomes from a multicentre randomized trial.Neurourology and urodynamics · 2021Trial
- Characteristics Associated With Treatment Failure 1 Year After Midurethral Sling in Women With Mixed Urinary Incontinence.Obstetrics and gynecology · 2020Trial
- Anesthetics' role in postoperative urinary retention after pelvic organ prolapse surgery with concomitant midurethral slings: a randomized clinical trial.International urogynecology journal · 2020Trial
- What is the optimal length for single-incision tape?International urogynecology journal · 2019Trial
160 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
31 authors at 16 institutions in 1 country.
Funding
Abstract
backgroundMidurethral slings are increasingly used for the treatment of stress incontinence, but there are limited data comparing types of slings and associated complications.
methodsWe performed a multicenter, randomized equivalence trial comparing outcomes with retropubic and transobturator midurethral slings in women with stress incontinence. The primary outcome was treatment success at 12 months according to both objective criteria (a negative stress test, a negative pad test, and no retreatment) and subjective criteria (self-reported absence of symptoms, no leakage episodes recorded, and no retreatment). The predetermined equivalence margin was +/-12 percentage points.
resultsA total of 597 women were randomly assigned to a study group; 565 (94.6%) completed the 12-month assessment. The rates of objectively assessed treatment success were 80.8% in the retropubic-sling group and 77.7% in the transobturator-sling group (3.0 percentage-point difference; 95% confidence interval [CI], -3.6 to 9.6). The rates of subjectively assessed success were 62.2% and 55.8%, respectively (6.4 percentage-point difference; 95% CI, -1.6 to 14.3). The rates of voiding dysfunction requiring surgery were 2.7% in those who received retropubic slings and 0% in those who received transobturator slings (P=0.004), and the respective rates of neurologic symptoms were 4.0% and 9.4% (P=0.01). There were no significant differences between groups in postoperative urge incontinence, satisfaction with the results of the procedure, or quality of life.
conclusionsThe 12-month rates of objectively assessed success of treatment for stress incontinence with the retropubic and transobturator approaches met the prespecified criteria for equivalence; the rates of subjectively assessed success were similar between groups but did not meet the criteria for equivalence. Differences in the complications associated with the two procedures should be discussed with patients who are considering surgical treatment for incontinence. (ClinicalTrials.gov number, NCT00325039.)
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.