Evidence map›Paper›PMID 20479164›Full record

ReviewCirculation2010

Cardiac titin: a multifunctional giant.

Martin M LeWinter, Henk Granzier

Abstract readReview
In one paragraph

Review in Circulation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 142 papers.

0numbers the graph read from it
0cells of the map it votes in
142citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

142 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Ceramide as a Biomarker for HFpEF in Women: Menopause, Aging, and Pregnancy.International journal of molecular sciences · 2025
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Understanding inherited cardiomyopathies: clinical aspects and genetic determinants.Medizinische Genetik : Mitteilungsblatt des Berufsverbandes Medizinische Genetik e.V · 2025
    Article
  18. Article
  19. Review
  20. Review

82 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Martin M LeWinterCardiology Unit, Fletcher Allen Health Care, 111 Colchester Ave, Burlington, VT 05401, USA. martin.lewinter@vtmednet.org
Henk Granzier

Funding

Function of Giant Sarcomere Matrix Proteins in MuscleR01HL062881 · NHLBI · WASHINGTON STATE UNIVERSITY · PI GRANZIER, HENK L. · 1999 to 2018
$6.4M
TITIN AND HEART FUNCTION AND DISEASE (INDIVIDUAL)R01HL061497 · NHLBI · WASHINGTON STATE UNIVERSITY · PI GRANZIER, HENK L. · 1998 to 2007
$3.3M
NHLBI NIH HHS HL062881NHLBI NIH HHS HL61497NHLBI NIH HHS R01 HL061497NHLBI NIH HHS R01 HL062881
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Actin CytoskeletonAnimalsConnectinHeartHeart DiseasesHumansMuscle ProteinsMyocardial ContractionMyocytes, CardiacProtein KinasesConnectinMuscle ProteinsProtein KinasesTTN protein, human

Identifiers

PMID20479164
PMCPMC2905226

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.