ArticlePediatrics2010
Infant weight gain and school-age blood pressure and cognition in former preterm infants.
Article in Pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Postnatal growth in preterm infants and later health outcomes: a systematic review.Acta paediatrica (Oslo, Norway : 1992) · 2015Pooled it
- Systematic review and meta-analysis of preterm birth and later systolic blood pressure.Hypertension (Dallas, Tex. : 1979) · 2012Pooled it
- Glucose-regulatory hormones and growth in very preterm infants fed fortified human milk.Pediatric research · 2024Trial
- Associations of fetal and infant growth patterns with behavior and cognitive outcomes in early adolescence.JCPP advances · 2025Article
- Establishing feasibility and reliability of subcutaneous fat measurements by ultrasound in very preterm infants.Pediatric research · 2024Article
- Impact of Early Ying Yang Bao Nutritional Support on Growth and Neurodevelopment in Preschool Children in China.Nutrients · 2024Article
- Association of Growth During Infancy with Neurodevelopment and Obesity in Children Born Very Preterm: The Environmental Influences on Child Health Outcomes Cohort.The Journal of pediatrics · 2024Article
- Growth During Infancy After Extremely Preterm Birth: Associations with Later Neurodevelopmental and Health Outcomes.The Journal of pediatrics · 2023Article
- Regulation of nephron progenitor cell lifespan and nephron endowment.Nature reviews. Nephrology · 2022Review
- Optimizing Early Neonatal Nutrition and Dietary Pattern in Premature Infants.International journal of environmental research and public health · 2021Review
- Impact of size at birth and postnatal growth on metabolic and neurocognitive outcomes in prematurely born school-age children.Scientific reports · 2021Article
- Review
- Postnatal nutritional intakes and hyperglycemia as determinants of blood pressure at 6.5 years of age in children born extremely preterm.Pediatric research · 2019Article
- Racial Disparities in Blood Pressure Trajectories of Preterm Children: The Role of Family and Neighborhood Socioeconomic Status.American journal of epidemiology · 2017Article
- Optimizing Nutrition in Preterm Low Birth Weight Infants-Consensus Summary.Frontiers in nutrition · 2017Review
- Long-term metabolic risk among children born premature or small for gestational age.Nature reviews. Endocrinology · 2017Review
- Parental Perceptions of Weight Status in Preterm Compared with Term Infants.American journal of perinatology · 2016Article
- Weight Status in the First 2 Years of Life and Neurodevelopmental Impairment in Extremely Low Gestational Age Newborns.The Journal of pediatrics · 2016Article
- Characteristics of systemic hypertension in preterm children.Journal of clinical hypertension (Greenwich, Conn.) · 2015Article
- Importance of characterizing growth trajectories.Annals of nutrition & metabolism · 2014Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesMore rapid infant weight gain may be associated with better neurodevelopment but also with higher blood pressure (BP). The objective of this study was to determine the extent to which infant weight gain is associated with systolic BP (SBP) and IQ at school age in former preterm, low birth weight infants.
methodsWe studied 911 participants in the Infant Health and Development Program, an 8-center longitudinal study of children born at < or = 37 weeks' gestation and < or = 2500 g. Study staff weighed participants at term and at 4 and 12 months' corrected ages; measured BP 3 times at 6.5 years; and administered the Wechsler Intelligence Scale for Children, Third Edition (WISC-III), an IQ test, at 8 years. In linear regression, we modeled our exposure "infant weight gain" as the 12-month weight z score adjusted for the term weight z score.
resultsMedian (interquartile range) weight z score was -0.7 (-1.5 to -0.0) at 12 months. Mean + or - SD SBP at 6.5 years was 104.2 + or - 8.4 mmHg, and mean + or - SD WISC-III total score at 8 years was 91 + or - 18. Adjusting for child gender, age, and race and maternal education, income, age, IQ, and smoking, for each z score additional weight gain from term to 12 months, SBP was 0.7 mmHg higher and WISC-III total score was 1.9 points higher.
conclusionsIn preterm infants, there seem to be modest neurodevelopmental advantages of more rapid weight gain in the first year of life and only small BP-related effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.