ArticleExpert review of respiratory medicine2009
Lung disease at high altitude.
Article in Expert review of respiratory medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 47 citations in OpenAlex.
- Effect of Nocturnal Oxygen on Blood Pressure Response to Altitude Exposure in COPD - Data from a Randomized Placebo-Controlled Cross-Over Trial.International journal of chronic obstructive pulmonary diseaseTrial
- Comparative analysis of pulmonary function in diverse ethnic adults living at low and high altitudes.Respiratory research · 2025Observational
- Acute mountain sickness prediction: a concerto of multidimensional phenotypic data and machine learning strategies in the framework of predictive, preventive, and personalized medicine.The EPMA journal · 2025Article
- High-altitude pulmonary hypertension: a comprehensive review of mechanisms and management.Clinical and experimental medicine · 2025Review
- The Effect of Chronic Altitude Exposure on Chronic Obstructive Pulmonary Disease Outcomes in the SPIROMICS Cohort: An Observational Cohort Study.American journal of respiratory and critical care medicine · 2024Observational
- Recent public health concerns of the high-altitude tribal population of Lahaul and Spiti, Himachal Pradesh.Journal of family medicine and primary care · 2023Article
- Underlying lung disease and exposure to terrestrial moderate and high altitude: personalised risk assessment.BMC pulmonary medicine · 2022Review
- Case Report: Misdiagnosis of Lung Carcinoma in Patients with Shrunken Lung Cyst After High Altitude Travel.Cancer management and research · 2022Article
- Effects of Altitude on Chronic Obstructive Pulmonary Disease Patients: Risks and Care.Life (Basel, Switzerland) · 2021Review
- Exposomes to Exosomes: Exosomes as Tools to Study Epigenetic Adaptive Mechanisms in High-Altitude Humans.International journal of environmental research and public health · 2021Review
- Secondary polycythemia in chronic obstructive pulmonary disease: prevalence and risk factors.BMC pulmonary medicine · 2021Observational
- Red blood cell exchange for SARS-CoV-2: A Gemini of therapeutic opportunities.Medical hypotheses · 2020Article
- How Do COVID-19 Inpatients in the Denver Metropolitan Area Measure Up?Advances in medicine · 2020Article
- Determinants of Acute Respiratory Infection Among Children in Ethiopia: A Multilevel Analysis from Ethiopian Demographic and Health Survey.International journal of general medicine · 2020Article
- Participation of the miR-22-HDAC4-DLCO Axis in Patients with COPD by Tobacco and Biomass.Biomolecules · 2019Article
- Recommendations for travelling with bronchiectasis: a joint ELF/EMBARC/ERN-Lung collaboration.ERJ open research · 2019Article
- Should I stay or should I go? COPD and air travel.European respiratory review : an official journal of the European Respiratory Society · 2018Review
- The protective role of 5-hydroxymethyl-2-furfural (5-HMF) against acute hypobaric hypoxia.Cell stress & chaperones · 2011Article
- The lung at high altitude.Multidisciplinary respiratory medicine · 2011Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Large numbers of people travel to high altitudes, entering an environment of hypobaric hypoxia. Exposure to low oxygen tension leads to a series of important physiologic responses that allow individuals to tolerate these hypoxic conditions. However, in some cases hypoxia triggers maladaptive responses that lead to various forms of acute and chronic high altitude illness, such as high-altitude pulmonary edema or chronic mountain sickness. Because the respiratory system plays a critical role in these adaptive and maladaptive responses, patients with underlying lung disease may be at increased risk for complications in this environment and warrant careful evaluation before any planned sojourn to higher altitudes. In this review, we describe respiratory disorders that occur with both acute and chronic exposures to high altitudes. These disorders may occur in any individual who ascends to high altitude, regardless of his/her baseline pulmonary status. We then consider the safety of high-altitude travel in patients with various forms of underlying lung disease. The available data regarding how these patients fare in hypoxic conditions are reviewed, and recommendations are provided for management prior to and during the planned sojourn.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.