Evidence map›Paper›PMID 20477275›Full record

ArticleExpert review of respiratory medicine2007

Circulating progenitor cells in chronic lung disease.

Borna Mehrad, Michael P Keane, Brigitte N Gomperts, Robert M Strieter

Open access · greenAbstract read
In one paragraph

Article in Expert review of respiratory medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Matrix control of scarring.Cellular and molecular life sciences : CMLS · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Borna MehradUniversity of Virginia, Division of Pulmonary & Critical Care Medicine, Department of Medicine, Box 800546, Charlottesville, VA 22908, USA. mehrad@virginia.edu
Michael P Keane
Brigitte N Gomperts
Robert M Strieter
University of California, Los Angeles · USUniversity of Virginia · US

Funding

CXC Chemokines in CancerR01CA087879 · NCI · UNIVERSITY OF VIRGINIA · PI STRIETER, ROBERT M · 2000 to 2010
$3.4M
NK cells in host defense against invasive aspergillosisR01HL073848 · NHLBI · UNIVERSITY OF VIRGINIA · PI MEHRAD, BORNA · 2003 to 2013
$3.3M
Chemokines and Fibrocytes in Acute Lung InjuryR01HL066027 · NHLBI · UNIVERSITY OF VIRGINIA · PI STRIETER, ROBERT M · 2001 to 2009
$3.2M
CYTOKINES AS PREDICTORS OF DISEASE PROGRESSION IN SCLERODERMA LUNG DISEASER01AR055075 · NIAMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROTH, MICHAEL D · 2006 to 2009
$1.3M
NCI NIH HHS R01 CA087879NHLBI NIH HHS R01 HL066027NHLBI NIH HHS R01 HL073848NIAMS NIH HHS R01 AR055075
6 · The paper itself

Abstract

Tissue regeneration and repair are fundamental both to recovery of the lung from injury and to the pathology of many chronic lung diseases. There are two potential sources for the adult progenitor cells that participate in this reparative process: resident lung progenitors and bone marrow-derived circulating cells. Bone marrow-derived cells, in particular, have been shown to give rise to airway and alveolar epithelial cells, as well as lung mesenchymal cells. Emerging data have linked specific chemokine ligand-receptor interactions to the recruitment of these cells to the lung and has implicated these cells in chronic lung disorders such as asthma and interstitial lung diseases. In this review, we summarize the current understanding of the biology of adult circulating progenitors as related to lung disease.

Identifiers

PMID20477275
PMCPMC3353522
OpenAlexW2098945043

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.