Evidence map›Paper›PMID 20476790›Full record

ArticleJournal of the American Chemical Society2010

Polyketide assembly by alkene-alkyne reductive cross-coupling: spiroketals through the union of homoallylic alcohols.

Daniel P Canterbury, Glenn C Micalizio

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Enantiospecific Alkynylation of Alkylboronic Esters.Angewandte Chemie (International ed. in English) · 2016
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Daniel P CanterburyDepartment of Chemistry, The Scripps Research Institute, Scripps Florida, Jupiter, Florida 33458, USA.
Glenn C Micalizio

Funding

Stereoselective Synthesis via Metallacycle-Mediated Bond ConstructionR01GM080266 · NIGMS · YALE UNIVERSITY · PI MICALIZIO, GLENN C · 2007 to 2019
$4.8M
NIGMS NIH HHS GM80266NIGMS NIH HHS R01 GM080266
6 · The paper itself

Abstract

A reaction sequence composed of regioselective formal hydroalkynylation, reductive ene-yne cross-coupling, and oxidative cyclization has been developed to prepare stereochemically dense spiroketals. Overall, the chemistry defines a three-component coupling process for the union of two homoallylic alcohol-based substrates with trimethylsilylacetylene.

Indexed as

AlcoholsAlkenesAlkynesCyclizationFuransOxidation-ReductionSpiro CompoundsStereoisomerismAlcoholsAlkenesAlkynesFuransSpiro Compoundsspiroketal

Identifiers

PMID20476790
PMCPMC2892691

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.