Evidence map›Paper›PMID 20472805›Full record

ArticleVeterinary pathology2010

The histopathologic and molecular basis for the diagnosis of histiocytic sarcoma and histiocyte-associated lymphoma of mice.

X Hao, T N Fredrickson, S K Chattopadhyay, W Han, C-F Qi, Z Wang, J M Ward, J W Hartley, H C Morse

Abstract read
In one paragraph

Article in Veterinary pathology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 33 citations in OpenAlex.

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  10. Hematopoietic neoplasms in Prkar2a-deficient mice.Journal of experimental & clinical cancer research : CR · 2015
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

X HaoLaboratory of Immunopathology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.
T N Fredrickson
S K Chattopadhyay
W Han
C-F Qi
Z Wang
J M Ward
J W Hartley
H C Morse
National Institute of Allergy and Infectious Diseases · USNational Cancer Institute · USNational Institutes of Health · USRutgers, The State University of New Jersey · US

Funding

Molecular Regulation of B-Cell Differentiation and FunctionZIAAI001024 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MORSE, HERBERT · 2009 to 2018
$8.3M
Lymphomas And Retroviral PathogenesisZIAAI000858 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MORSE, HERBERT · 2009 to 2018
$5.3M
Intramural NIH HHS Z99 AI999999Intramural NIH HHS ZIA AI000858NIAID NIH HHS Y99 AI999999
6 · The paper itself

Abstract

Histiocytic sarcoma (HS) and histiocyte-associated lymphoma (HAL) of mice are difficult to distinguish histologically. Studies of multiple cases initially diagnosed as HS or HAL allowed us to define HS as round, fusiform, or mixed cell types that were F4/80+, Mac-2+, and PAX5-; that lacked markers for other sarcomas; and that had immune receptor genes in germline configuration. Two other subsets had clonal populations of lymphocytes. The first, HAL, featured malignant lymphocytes admixed with large populations of normal-appearing histiocytes. The second appeared to be composites of lymphoma and HS. Several cases suggestive of B myeloid-lineage plasticity were also observed.

Indexed as

MiceAnimalsAntigens, DifferentiationBiomarkers, TumorFemaleGalectin 3Histiocytic SarcomaLymphomaMaleMuramidasePAX5 Transcription FactorRodent DiseasesAntigens, DifferentiationBiomarkers, TumorGalectin 3monocyte-macrophage differentiation antigenMuramidasePax5 protein, mousePAX5 Transcription Factor

Identifiers

PMID20472805
PMCPMC3407882
OpenAlexW2160832005

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.