ReviewEukaryotic cell2010
Microtubule-dependent mRNA transport in fungi.
Review in Eukaryotic cell, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 43 citations in OpenAlex.
- Spatiotemporal regulation of arbuscular mycorrhizal symbiosis at cellular resolution.The Plant cell · 2026Article
- smFISH for Plants.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Metabolic Changes and Antioxidant Response inJournal of fungi (Basel, Switzerland) · 2023Article
- Kinesin Motors in the Filamentous Basidiomycetes in Light of theJournal of fungi (Basel, Switzerland) · 2022Review
- The GUL-1 Protein Binds Multiple RNAs Involved in Cell Wall Remodeling and Affects the MAK-1 Pathway inFrontiers in fungal biology · 2021Article
- Article
- Life as a moving fluid: fate of cytoplasmic macromolecules in dynamic fungal syncytia.Current opinion in microbiology · 2015Review
- A FYVE zinc finger domain protein specifically links mRNA transport to endosome trafficking.eLife · 2015Article
- Plant architecture without multicellularity: quandaries over patterning and the soma-germline divide in siphonous algae.Frontiers in plant science · 2015Article
- Early endosome motility spatially organizes polysome distribution.The Journal of cell biology · 2014Article
- Rhinanthus serotinus (Schönheit) Oborny (Scrophulariaceae): immunohistochemical and ultrastructural studies of endosperm chalazal haustorium development.Protoplasma · 2013Article
- mRNA localization mechanisms in Trypanosoma cruzi.PloS one · 2013Article
- Microtubule-dependent membrane dynamics in Ustilago maydis: Trafficking and function of Rab5a-positive endosomes.Communicative & integrative biology · 2012Article
- Principles and roles of mRNA localization in animal development.Development (Cambridge, England) · 2012Review
- Principles of mRNA transport in yeast.Cellular and molecular life sciences : CMLS · 2012Review
- Assembly of mRNA-protein complexes for directional mRNA transport in eukaryotes--an overview.Current protein & peptide science · 2012Review
- Control of cytoplasmic mRNA localization.Cellular and molecular life sciences : CMLS · 2012Review
- The RNA-binding protein Rrm4 is essential for efficient secretion of endochitinase Cts1.Molecular & cellular proteomics : MCP · 2011Article
- Nuclear and genome dynamics in multinucleate ascomycete fungi.Current biology : CB · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The localization and local translation of mRNAs constitute an important mechanism to promote the correct subcellular targeting of proteins. mRNA localization is mediated by the active transport of mRNPs, large assemblies consisting of mRNAs and associated factors such as RNA-binding proteins. Molecular motors move mRNPs along the actin or microtubule cytoskeleton for short-distance or long-distance trafficking, respectively. In filamentous fungi, microtubule-based long-distance transport of vesicles, which are involved in membrane and cell wall expansion, supports efficient hyphal growth. Recently, we discovered that the microtubule-mediated transport of mRNAs is essential for the fast polar growth of infectious filaments in the corn pathogen Ustilago maydis. Combining in vivo UV cross-linking and RNA live imaging revealed that the RNA-binding protein Rrm4, which constitutes an integral part of the mRNP transport machinery, mediates the transport of distinct mRNAs encoding polarity factors, protein synthesis factors, and mitochondrial proteins. Moreover, our results indicate that microtubule-dependent mRNA transport is evolutionarily conserved from fungi to higher eukaryotes. This raises the exciting possibility of U. maydis as a model system to uncover basic concepts of long-distance mRNA transport.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.