ReviewNeurobiology of disease2010
Modeling mitochondrial encephalomyopathy in Drosophila.
Review in Neurobiology of disease, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Article
- Advances in mt-tRNA Mutation-Caused Mitochondrial Disease Modeling: Patients' Brain in a Dish.Frontiers in genetics · 2020Review
- Ketogenic and anaplerotic dietary modifications ameliorate seizure activity in Drosophila models of mitochondrial encephalomyopathy and glycolytic enzymopathy.Molecular genetics and metabolism · 2019Article
- Sleep and circadian defects in aNeurobiology of sleep and circadian rhythms · 2019Article
- Protein coding mitochondrial-targeted RNAs rescue mitochondrial disease in vivo.Neurobiology of disease · 2018Article
- Small mitochondrial-targeted RNAs modulate endogenous mitochondrial protein expression in vivo.Neurobiology of disease · 2014Article
- The alternative oxidase AOX does not rescue the phenotype of tko25t mutant flies.G3 (Bethesda, Md.) · 2014Article
- Genetically encoded redox sensor identifies the role of ROS in degenerative and mitochondrial disease pathogenesis.Neurobiology of disease · 2012Article
- Modes of metabolic compensation during mitochondrial disease using the Drosophila model of ATP6 dysfunction.PloS one · 2011Article
- The ATP-sensitive K channel is seizure protective and required for effective dietary therapy in a model of mitochondrial encephalomyopathy.Journal of neurogeneticsArticle
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Mitochondrial encephalomyopathies are disturbingly complex and devastating diseases, reflecting the underlying importance of the affected organelle. Therapeutic approaches for these diseases remain limited due to a poor understanding of disease pathogenesis resulting largely from a lack of tractable model systems in which to study these diseases. This is especially so for disease conditions resulting from mutations directly affecting the mitochondrial genome. Recent studies using Drosophila to develop genetic models with endogenous mitochondrial mutations suggest the fruit fly will contribute significantly to our understanding of mitochondrial disease pathogenesis and the development of novel therapeutic avenues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.