Evidence map›Paper›PMID 20471240›Full record

ReviewCurrent opinion in neurobiology2010

Joining the dots: from chromatin remodeling to neuronal plasticity.

Loredana Zocchi, Paolo Sassone-Corsi

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Epigenetics of neural differentiation: Spotlight on enhancers.Frontiers in cell and developmental biology · 2022
    Review
  4. Article
  5. Review
  6. Article
  7. Epigenetic Etiology of Intellectual Disability.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. BDNF deregulation in Rett syndrome.Neuropharmacology · 2014
    Review
  17. Review
  18. Acetyltransferases (HATs) as targets for neurological therapeutics.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2013
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Loredana ZocchiDepartment of Pharmacology, School of Medicine, University of California-Irvine, Irvine CA 92697, USA.
Paolo Sassone-Corsi

Funding

Chromatin Remodeling and Circadian Clock ControlR01GM081634 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI SASSONE-CORSI, PAOLO · 2007 to 2011
$1.6M
NIGMS NIH HHS R01 GM081634
6 · The paper itself

Abstract

In recent years spectacular advances in the field of epigenetics have taken place. Multiple lines of evidence that connect epigenetic regulation to brain functions have been accumulating. Neurons daily convert a variety of external stimuli into rapid or long-lasting changes in gene expression. Control is achieved through several covalent modifications that occur both on DNA and chromatin. Specific modifications mediate many developmental processes and adult brain functions, such as synaptic plasticity and memory. In this review, we focus on crucial chromatin remodeling events that mediate long-lasting neuronal responses. The challenging goal is to reach sufficient understanding of these epigenetic pathways in the brain so that they may be useful for future development of specific pharmacological strategies.

Indexed as

AnimalsBrainChromatin Assembly and DisassemblyEpigenesis, GeneticHumansNeuronal PlasticityNeuronsSignal Transduction

Identifiers

PMID20471240
PMCPMC3375208

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.