ArticlePediatric nephrology (Berlin, Germany)2010
Vesicoureteral reflux in children with suspected and proven urinary tract infection.
Article in Pediatric nephrology (Berlin, Germany), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Dimercaptosuccinic acid scan or ultrasound in screening for vesicoureteral reflux among children with urinary tract infections.The Cochrane database of systematic reviews · 2016Pooled it
- Antibiotic prophylaxis in the management of vesicoureteric reflux: a randomized double-blind placebo-controlled trial.Pediatric nephrology (Berlin, Germany) · 2015Trial
- Abnormal Ultrasound Findings After a Urinary Tract Infection in Children.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Prediction model for severe vesicoureteral reflux in children with urinary tract infection and/or hydronephrosis.Pediatric nephrology (Berlin, Germany) · 2025Article
- What paediatricians need to know about modern urologic management of vesicoureteral reflux.Frontiers in pediatrics · 2025Review
- Primary vesicoureteral reflux.Nature reviews. Disease primers · 2024Review
- Ultrasound-based predictive indicators for treatment outcomes in pediatric vesicoureteral reflux.Surgery today · 2024Article
- Comparison and clinical analysis of antibiotics and endoscopic injection for vesicoureteral reflux in children.Pediatric surgery international · 2024Article
- A quantitative analysis of voiding cystourethrogram features confirms the association between high-grade vesicoureteral reflux with male sex, younger age, and hydronephrosis.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2023Article
- Risk factors for kidney scarring and vesicoureteral reflux in 421 children after their first acute pyelonephritis, and appraisal of international guidelines.Pediatric nephrology (Berlin, Germany) · 2021Article
- Imaging in Febrile Urinary Tract Infections - Area of Debate.Indian journal of pediatrics · 2020Article
- Urinary tract infections in children.Lancet (London, England) · 2020Review
- Optimal bacterial colony counts for the diagnosis of upper urinary tract infections in infants.Clinical and experimental nephrology · 2020Observational
- Parent compliance: a bad predictor of resolution and a problem in the application of EAU guidelines on vesicoureteral reflux in children.International urology and nephrology · 2017Article
- [Vesico-ureteral reflux: Diagnosis and treatment recommendations].Der Urologe. Ausg. A · 2016Review
- Anatomy and Physiology of the Urinary Tract: Relation to Host Defense and Microbial Infection.Microbiology spectrum · 2015Review
- Escherichia coli biofilm formation and recurrences of urinary tract infections in children.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014Article
- Does the ureteric jet Doppler waveform have a role in detecting vesicoureteric reflux?Pediatric nephrology (Berlin, Germany) · 2013Article
- History of recurrent urinary tract infection is not predictive of abnormality on voiding cystourethrogram.Pediatric surgery international · 2013Article
- [Primary vesicoureteral reflux].Der Urologe. Ausg. A · 2013Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to estimate the prevalence of vesicoureteral reflux (VUR) and clinically significant ultrasonography (US) abnormalities in a large group of children with proven and suspected urinary tract infection (UTI). The medical reports on renal US and voiding cystouretrographies (VCUG) of 2,036 children were reviewed. Renal US was performed on all children and VCUG on 1,185 children (58%). Based on the urine culture data, the UTI diagnoses were classified into five reliability classes (proven, likely, unlikely, false and no microbial data). The UTI diagnose was considered proven in 583/2036 (28.6%) and false in 145 (7.1%) cases. The prevalence of VUR was similar among those with proven and false UTI [37.4 vs. 34.8%; relative risk (RR) 1.08, 95% confidence intervals (95% CI) 0.7-1.7, P = 0.75] and decreased with increasing age (P = 0.001). Clinically significant US abnormalities occurred in 87/583 (14.9%) cases with proven UTI and significantly less often (11/145, 7.6%) in the false UTI class (RR 1.96, 95% CI 1.1-3.6, P = 0.02). Our finding supports the claim that VUR is not significantly associated to UTI and that its occurrence among children even without UTI is significantly higher than traditional estimates. This challenges the recommendations of routine VCUG after UTI.
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