ArticleInternational journal of body composition research2009
Validation of quantitative magnetic resonance for the determination of body composition of mice.
Article in International journal of body composition research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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Who cites it
25 citing papers in PubMed.
- Article
- The hummingbird's adipostat: can a simple rule explain torpor frequency and duration in hummingbirds?Proceedings. Biological sciences · 2025Article
- Impact of sustained calorie restriction and weight cycling on body composition in high-fat diet-fed male and female C57BL/6J mice.Obesity (Silver Spring, Md.) · 2024Article
- Inferring condition in wild mammals: body condition indices confer no benefit over measuring body mass across ecological contexts.Oecologia · 2024Article
- Adipocyte-Specific Modulation of KLF14 Expression in Mice Leads to Sex-Dependent Impacts on Adiposity and Lipid Metabolism.Diabetes · 2022Article
- S-allylmercaptocysteine improves nonalcoholic steatohepatitis by enhancing AHR/NRF2-mediated drug metabolising enzymes and reducing NF-κB/IκBα and NLRP3/6-mediated inflammation.European journal of nutrition · 2021Article
- Strengths and validity of three methods for assessing rat body fat across the life course.International journal of obesity (2005) · 2020Article
- Genetic Deletion ofNutrients · 2019Article
- Burly1 is a mouse QTL for lean body mass that maps to a 0.8-Mb region of chromosome 2.Mammalian genome : official journal of the International Mammalian Genome Society · 2018Article
- No Significant Effect of Maternal Perception of the Food Environment on Reproductive Success or Pup Outcomes in C57BL/6J Mice.Obesity (Silver Spring, Md.) · 2018Article
- Article
- Reliability of the EchoMRI Infants System for Water and Fat Measurements in Newborns.Obesity (Silver Spring, Md.) · 2017Article
- Validation of Body Condition Indices and Quantitative Magnetic Resonance in Estimating Body Composition in a Small Lizard.Journal of experimental zoology. Part A, Ecological genetics and physiology · 2016Article
- In Vivo Determination of Body Composition in Zebrafish (Danio rerio) by Quantitative Magnetic Resonance.Zebrafish · 2016Article
- Correlation of X-ray computed tomography with quantitative nuclear magnetic resonance methods for pre-clinical measurement of adipose and lean tissues in living mice.Sensors (Basel, Switzerland) · 2014Article
- Variations in body weight, food intake and body composition after long-term high-fat diet feeding in C57BL/6J mice.Obesity (Silver Spring, Md.) · 2014Article
- Carnitine Palmitoyltransferase 1b Deficiency Protects Mice from Diet-Induced Insulin Resistance.Journal of diabetes & metabolism · 2014Article
- Measurement of interscapular brown adipose tissue of mice in differentially housed temperatures by chemical-shift-encoded water-fat MRI.Journal of magnetic resonance imaging : JMRI · 2013Article
- Leptin resistance is a secondary consequence of the obesity in ciliopathy mutant mice.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Quantitative trait loci affecting liver fat content in mice.G3 (Bethesda, Md.) · 2012Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
objectiveThe aim of this study was to assess the precision and accuracy of a quantitative magnetic resonance (QMR) instrument for measuring body composition in live, non-anesthetized mice.
methodsForty-eight mice of varying strains, ages and body weights (15.3 to 50.2g) were scanned three times each in the QMR instrument. Animals were killed and chemical carcass analysis performed for comparison. Precision was assessed as the coefficient of variation (CV) for the triplicate scans and accuracy was determined by comparing the first QMR data with the chemical analysis. Prediction equations were generated by linear regression analysis and used in a cross-validation study in which 26 mice were scanned once each, killed, and chemical carcass analysis performed.
resultsThe mean CV was 1.58% for fat mass (FM) and 0.78% for lean-tissue mass (LTM). QMR significantly (P<0.01) overestimated FM (7.76±5.93 vs. 6.03±5.17g) and underestimated LTM (20.73±6.19 vs. 22.48±6.75g) when compared with chemical carcass analysis. A strong relationship between QMR and chemical data (r(2)=0.99 and r(2)=0.97 for fat and LTM respectively; P<0.0001) allowed for the generation of correction equations that were applied to QMR data in the cross-validation study. There was no significant difference between data predicted from QMR and chemical carcass data for FM and LTM (P=0.15 and 0.10 respectively).
conclusionThe QMR instrument showed excellent precision and data was highly correlated with chemical carcass analysis. This combined with QMR's speed for whole animal analysis (95 seconds) make it a highly feasible and useful method for the determination of body composition in live, non-anesthetized mice.
Identifiers
20467582PMC2868277What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.