ArticleCardiopulmonary physical therapy journal2009
The effects of a twelve-week home walking program on cardiovascular parameters and fatigue perception of individuals with multiple sclerosis: a pilot study.
Article in Cardiopulmonary physical therapy journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Which exercise and behavioural interventions show most promise for treating fatigue in multiple sclerosis? A network meta-analysis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2021Pooled it
- Behavior Change Techniques in Physical Activity Interventions for Multiple Sclerosis.Archives of physical medicine and rehabilitation · 2021Pooled it
- Walking for hypertension.The Cochrane database of systematic reviews · 2021Pooled it
- Exercise therapy for fatigue in multiple sclerosis.The Cochrane database of systematic reviews · 2015Pooled it
- Effectiveness of non-pharmacological interventions for fatigue in long term conditions: systematic review and network meta-analysis.BMJ medicine · 2026Article
- The effect of exercise and physical activity-interventions on step count and intensity level in individuals with multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials.Frontiers in sports and active living · 2023Review
- Systematic Review of Exercise Studies in Persons with Multiple Sclerosis: Exploring the Quality of Interventions According to the Principles of Exercise Training.Neurology and therapy · 2021Review
- Response Heterogeneity With Exercise Training and Physical Activity Interventions Among Persons With Multiple Sclerosis.Neurorehabilitation and neural repair · 2019Review
- The Efficacy of Psychological Interventions for Managing Fatigue in People With Multiple Sclerosis: A Systematic Review and Meta-Analysis.Frontiers in neurology · 2018Article
- A combined exercise model for improving muscle strength, balance, walking distance, and motor agility in multiple sclerosis patients: A randomized clinical trial.Iranian journal of neurology · 2016Article
- Effects of walking-induced fatigue on gait function and tripping risks in older adults.Journal of neuroengineering and rehabilitation · 2014Article
- The benefits of exercise training in multiple sclerosis.Nature reviews. Neurology · 2012Review
- Walking: the first steps in cardiovascular disease prevention.Current opinion in cardiology · 2010Review
- Functional intermuscular reduction in spasticity for people with multiple sclerosis.Multiple sclerosis journal - experimental, translational and clinicalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the effects of a 12-week home walking program on cardiovascular parameters, fatigue perception, and walking distance in persons with multiple sclerosis (MS).
methodsTwelve ambulatory persons with MS, not currently participating in exercise were randomly assigned to control (C) or experimental groups (EX). Pretest data collection included resting HR, BP, fatigue perception (Fatigue Severity Scale), and 6-minute walk test. EX received a home walking program (30 min, 3 x week, x 12 weeks), using a modification of Karvonen's formula to calculate HR range. A HR monitor was used to adjust walking speed. The C group refrained from any regular exercise. Posttest data were collected at week 12 and analyzed using the Mann-Whitney U Test.
resultsNo statistically significant differences were noted between groups in any measured parameters; however, walking distance and Physiologic Cost Index did improve in the exercise group.
conclusionNo adverse events or increase in fatigue levels related to the exercise intervention were reported in this study. This home walking program may not be of sufficient intensity to elicit significant cardiovascular changes. Abnormal cardiac responses have been documented in this population, which may have affected the results. Clinicians may need to use alternate measures to assess fitness in this population.
Indexed as
Identifiers
20467528PMC2845260W1602829472What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.