Evidence map›Paper›PMID 20467445›Full record

ArticleNature reviews. Microbiology2010

Molecular mechanisms of complement evasion: learning from staphylococci and meningococci.

Davide Serruto, Rino Rappuoli, Maria Scarselli, Piet Gros, Jos A G van Strijp

Abstract read
PubMed Publisher
In one paragraph

Article in Nature reviews. Microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. International journal of molecular sciences · 2025
    Article
  5. Review
  6. Pathogens (Basel, Switzerland) · 2025
    Review
  7. Characterization ofMicroorganisms · 2025
    Article
  8. Article
  9. Review
  10. Electron-Beam-KilledVaccines · 2024
    Article
  11. Article
  12. Article
  13. Yersinia pestis ΔApplied and environmental microbiology · 2023
    Article
  14. Article
  15. Review
  16. Frontiers in immunology · 2020
    Article
  17. Article
  18. Article
  19. Review
  20. Role of the Complement System in the Response to Orthopedic Biomaterials.International journal of molecular sciences · 2018
    Review

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Davide SerrutoNovartis Vaccines and Diagnostics, Via Fiorentina 1, 53100 Siena, Italy.
Rino Rappuoli
Maria Scarselli
Piet Gros
Jos A G van Strijp

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The complement system is a crucial component of the innate immune response in humans. Recent studies in Staphylococcus aureus and Neisseria meningitidis have revealed how these bacteria escape complement-mediated killing. In addition, new structural data have provided detailed insights into the molecular mechanisms of host defence mediated by the complement system and how bacterial proteins interfere with this process. This information is fundamental to our understanding of bacterial pathogenesis and may facilitate the design of better vaccines.

Indexed as

Immune EvasionBacterial ProteinsComplement Membrane Attack ComplexComplement System ProteinsCytoplasmImmunity, InnateMembrane ProteinsNeisseria meningitidisProtein ConformationStaphylococcus aureusVacuolesBacterial ProteinsComplement Membrane Attack ComplexComplement System ProteinsMembrane Proteins

Identifiers

PMID20467445

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.