ArticleBMC evolutionary biology2010
Duplication, concerted evolution and purifying selection drive the evolution of mosquito vitellogenin genes.
Article in BMC evolutionary biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Vitellogenin genes are transcribed in Culex quinquefasciatus ovary.Memorias do Instituto Oswaldo Cruz · 2023Article
- Transcriptome Expression of Biomineralization Genes in Littoraria flava Gastropod in Brazilian Rocky Shore Reveals Evidence of Local Adaptation.Genome biology and evolution · 2021Article
- Physical Mapping of theInsects · 2021Article
- RNAi-mediated silencing of vitellogenin gene curtails oogenesis in the almond moth Cadra cautella.PloS one · 2021Article
- Fat body-specific vitellogenin expression regulates host-seeking behaviour in the mosquito Aedes albopictus.PLoS biology · 2019Article
- Proteogenomics of Gammarus fossarum to document the reproductive system of amphipods.Molecular & cellular proteomics : MCP · 2014Article
- 20-hydroxyecdysone mediates non-canonical regulation of mosquito vitellogenins through alternative splicing.Insect molecular biology · 2014Article
- Culex tarsalis vitellogenin gene promoters investigated in silico and in vivo using transgenic Drosophila melanogaster.PloS one · 2014Article
- Tracing back the nascence of a new sex-determination pathway to the ancestor of bees and ants.Nature communications · 2012Article
- Vitellogenin gene expression in autogenous Culex tarsalis.Insect molecular biology · 2010Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundMosquito vitellogenin (Vtg) genes belong to a small multiple gene family that encodes the major yolk protein precursors required for egg production. Multiple Vtg genes have been cloned and characterized from several mosquito species, but their origin and molecular evolution are poorly understood.
resultsHere we used in silico and molecular cloning techniques to identify and characterize the evolution of the Vtg gene family from the genera Culex, Aedes/Ochlerotatus, and Anopheles. We identified the probable ancestral Vtg gene among different mosquito species by its conserved association with a novel gene approximately one kilobase upstream of the start codon. Phylogenetic analysis indicated that the Vtg gene family arose by duplication events, but that the pattern of duplication was different in each mosquito genera. Signatures of purifying selection were detected in Culex, Aedes and Anopheles. Gene conversion is a major driver of concerted evolution in Culex, while unequal crossover is likely the major driver of concerted evolution in Anopheles. In Aedes, smaller fragments have undergone gene conversion events.
conclusionsThe study shows concerted evolution and purifying selection shaped the evolution of mosquito Vtg genes following gene duplication. Additionally, similar evolutionary patterns were observed in the Vtg genes from other invertebrate and vertebrate organisms, suggesting that duplication, concerted evolution and purifying selection may be the major evolutionary forces driving Vtg gene evolution across highly divergent taxa.
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