Evidence map›Paper›PMID 20465393›Full record

ReviewFuture oncology (London, England)2010

Mechanism of lymph node metastasis in prostate cancer.

Kaustubh Datta, Michael Muders, Heyu Zhang, Donald J Tindall

Open access · greenAbstract readReview
In one paragraph

Review in Future oncology (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 108 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. SMC4 Promotes Prostate Cancer Cell Proliferation and Metastasis via the Rheb/mTOR Pathway.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Pharmacokinetic Study of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles HY-088 in Rats.European journal of drug metabolism and pharmacokinetics · 2024
    Article
  17. Article
  18. Article
  19. Article
  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Kaustubh DattaDepartment of Biochemistry & Molecular Biology, Gugg 17-93, Mayo Clinic Foundation, Rochester, MN 55905, USA. datta.kaustubh@mayo.edu
Michael Muders
Heyu Zhang
Donald J Tindall
Mayo Clinic · USUniversity Hospital Carl Gustav Carus · DE

Funding

Utility of serum and Tissue Biomarkers for Predicting Response to Androgen DeprivP50CA091956 · NCI · MAYO CLINIC ROCHESTER · PI TINDALL, DONALD J. · 2001 to 2010
$23.4M
The role of VEGF-C in resisting stress in prostate cancerR01CA140432 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI DATTA, KAUSTUBH · 2010 to 2014
$1.5M
Coregulators in Androgen-Refractory Prostate CancerR01CA121277 · NCI · MAYO CLINIC ROCHESTER · PI TINDALL, DONALD J. · 2006 to 2010
$1.3M
Androgenic Inactivation of FOXO1 in Prostate CancerR01CA125747 · NCI · MAYO CLINIC ROCHESTER · PI TINDALL, DONALD J. · 2007 to 2011
$1.3M
NCI NIH HHS CA 121277NCI NIH HHS CA 125747NCI NIH HHS CA 140432NCI NIH HHS CA 91956NCI NIH HHS P50 CA091956NCI NIH HHS R01 CA121277NCI NIH HHS R01 CA125747NCI NIH HHS R01 CA140432
6 · The paper itself

Abstract

Detection of lymph node metastases indicates poor prognosis for prostate cancer patients. Therefore, elucidation of the mechanism(s) of lymph node metastasis is important to understand the progression of prostate cancer and also to develop therapeutic interventions. In this article, the known mechanisms for lymph node metastasis are discussed and the involvement of lymphatic vessels in prostate cancer lymph node metastasis is comprehensively summarized. In addition, contradictory findings regarding the importance of lymphangiogenesis in facilitating lymph node metastasis in prostate cancer are pointed out and reconcilation is attempted.

Indexed as

HumansLymphangiogenesisLymphatic MetastasisMaleProstatic Neoplasms

Identifiers

PMID20465393
PMCPMC2892838
OpenAlexW2049909857

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.