SynthesisThe Cochrane database of systematic reviews2010
Speech and language therapy for aphasia following stroke.
Synthesis in The Cochrane database of systematic reviews, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06010030 (A Randomized Clinical Trial of tDCS to Remediate Phonological Impairment in Aphasia), which is not on this map. Cited by 40 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Clinical Trial of tDCS to Remediate Phonological Impairment in Aphasia
Who cites it
40 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Effectiveness and Safety of Butyphthalide Injection in Treatment of Aphasia after Cerebral Infarction: A Meta-analysis.Combinatorial chemistry & high throughput screening · 2026Pooled it
- Speech and language therapy for aphasia following stroke.The Cochrane database of systematic reviews · 2016Pooled it
- Glioma surgery in eloquent areas: can we preserve cognition?Acta neurochirurgica · 2016Pooled it
- Effect of low-frequency rTMS on aphasia in stroke patients: a meta-analysis of randomized controlled trials.PloS one · 2014Pooled it
- Differential Effects of Speech and Language Therapy and rTMS in Chronic Versus Subacute Post-stroke Aphasia: Results of the NORTHSTAR-CA Trial.Neurorehabilitation and neural repair · 2022Trial
- Trial
- Effectiveness of enhanced communication therapy in the first four months after stroke for aphasia and dysarthria: a randomised controlled trial.BMJ (Clinical research ed.) · 2012Trial
- Article
- Transcranial Alternating Current Stimulation as an Adjuvant for Nonfluent Aphasia: A Proof-of-Concept Study.Bioengineering (Basel, Switzerland) · 2026Article
- Article
- Prolonged intermittent theta burst stimulation for post-stroke aphasia: protocol of a randomized, double-blinded, sham-controlled trial.Frontiers in neurology · 2024Article
- Providing Functional Communication Test for Persian Patients and Determining Its Validity and Reliability.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Accuracy of rating scales for evaluating aphasic patients' psychological aspects and language function: A scoping review protocol.PloS one · 2023Article
- Speech Entrainment for Aphasia Recovery (SpARc) phase II trial design.Contemporary clinical trials communications · 2021Article
- Language training for oral and written naming impairment in primary progressive aphasia: a review.Translational neurodegeneration · 2021Review
- Enhancing Brain Plasticity to Promote Stroke Recovery.Frontiers in neurology · 2020Review
- Neural structures supporting spontaneous and assisted (entrained) speech fluency.Brain : a journal of neurology · 2019Article
- Treatment Response to a Double Administration of Constraint-Induced Language Therapy in Chronic Aphasia.Journal of speech, language, and hearing research : JSLHR · 2018Article
- Therapy-Induced Plasticity in Chronic Aphasia Is Associated with Behavioral Improvement and Time Since Stroke.Brain connectivity · 2018Article
- Assessment Fidelity in Aphasia Research.American journal of speech-language pathology · 2016Article
Corrections and comments
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- Update of
Authors and funding
3 authors.
Funding
Abstract
backgroundAphasia is an acquired language impairment following brain damage which affects some or all language modalities: expression and understanding of speech, reading and writing. Approximately one-third of people who have a stroke experience aphasia.
objectivesTo assess the effectiveness of speech and language therapy (SLT) for aphasia following stroke. SEARCH STRATEGY: We searched the Cochrane Stroke Group Trials Register (last searched April 2009), MEDLINE (1966 to April 2009) and CINAHL (1982 to April 2009). In an effort to identify further published, unpublished and ongoing trials we handsearched the International Journal of Language and Communication Disorders, searched reference lists of relevant articles and contacted other researchers and authors. SELECTION CRITERIA: Randomised controlled trials comparing SLT versus no SLT, SLT versus social support or stimulation, and one SLT intervention versus another SLT intervention. SLT refers to a formal speech and language therapy intervention that aims to improve language and communication abilities and in turn levels of communicative activity and participation. Social support and stimulation refers to an intervention which provides social support or communication stimulation but does not include targeted therapeutic interventions. Direct comparisons of different SLT interventions refers to SLT interventions that differ in terms of duration, intensity, frequency or method of intervention or in the theoretical basis for the SLT approach. DATA COLLECTION AND ANALYSIS: Two review authors independently extracted the data and assessed the quality of included trials. We sought missing data from study investigators if necessary. MAIN
resultsWe included 30 trials (41 paired comparisons) in the review: 14 subcomparisons (1064 participants) compared SLT with no SLT; six subcomparisons (279 participants) compared SLT with social support and stimulation; and 21 subcomparisons (732 participants) compared two approaches to SLT. In general, the trials randomised small numbers of participants across a range of characteristics (age, time since stroke and severity profiles), interventions and outcomes. Suitable statistical data were unavailable for several measures. AUTHORS'
conclusionsThis review shows some indication of the effectiveness of SLT for people with aphasia following stroke. We also observed a consistency in the direction of results which favoured intensive SLT over conventional SLT, though significantly more people withdrew from intensive SLT than conventional SLT. SLT facilitated by a therapist-trained and supervised volunteer appears to be as effective as the provision of SLT by a professional. There was insufficient evidence to draw any conclusions in relation to the effectiveness of one SLT approach over another.
Indexed as
Identifiers
20464716What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.