Evidence map›Paper›PMID 20464438›Full record

ArticleFunctional & integrative genomics2010

Fine mapping and syntenic integration of the semi-dwarfing gene sdw3 of barley.

Giang T H Vu, Thomas Wicker, Jan P Buchmann, Peter M Chandler, Takashi Matsumoto, Andreas Graner, Nils Stein

Abstract read
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In one paragraph

Article in Functional & integrative genomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. INDETERMINATE DOMAIN-DELLA protein interactions orchestrate gibberellin-mediated cell elongation in wheat and barley.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Fine mapping and gene cloning in the post-NGS era: advances and prospects.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020
    Review
  4. Article
  5. Major genes determining yield-related traits in wheat and barley.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017
    Review
  6. Article
  7. Article
  8. Fine mapping and identification of a candidate gene for the barley Un8 true loose smut resistance gene.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2015
    Article
  9. Review
  10. Article
  11. Genomics-based high-resolution mapping of the BaMMV/BaYMV resistance gene rym11 in barley (Hordeum vulgare L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2013
    Article
  12. Article
  13. High resolution mapping of Dense spike-ar (dsp.ar) to the genetic centromere of barley chromosome 7H.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2012
    Article
  14. Article
  15. Synteny between Brachypodium distachyon and Hordeum vulgare as revealed by FISH.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Giang T H VuLeibniz Institute of Plant Genetics and Crop Plant Research, Corrensstrasse 3, Gatersleben 06466, Germany.
Thomas Wicker
Jan P Buchmann
Peter M Chandler
Takashi Matsumoto
Andreas Graner
Nils Stein
Leibniz Institute of Plant Genetics and Crop Plant Research · DEUniversity of Zurich · CHCommonwealth Scientific and Industrial Research Organisation · AUInstitute of Agrobiological Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The barley mutant allele sdw3 confers a gibberellin-insensitive, semi-dwarf phenotype with potential for breeding of new semi-dwarfed barley cultivars. Towards map-based cloning, sdw3 was delimited by high-resolution genetic mapping to a 0.04 cM interval in a "cold spot" of recombination of the proximal region of the short arm of barley chromosome 2H. Extensive synteny between the barley Sdw3 locus (Hvu_sdw3) and the orthologous regions (Osa_sdw3, Sbi_sdw3, Bsy_sdw3) of three other grass species (Oryza sativa, Sorghum bicolor, Brachypodium sylvaticum) allowed for efficient synteny-based marker saturation in the target interval. Comparative sequence analysis revealed colinearity for 23 out of the 38, 35, and 29 genes identified in Brachypodium, rice, and Sorghum, respectively. Markers co-segregating with Hvu_sdw3 were generated from two of these genes. Initial attempts at chromosome walking in barley were performed with seven orthologous gene probes which were delimiting physical distances of 223, 123, and 127 kb in Brachypodium, rice, and Sorghum, respectively. Six non-overlapping small bacterial artificial chromosome (BAC) clone contigs (cumulative length of 670 kb) were obtained, which indicated a considerably larger physical size of Hvu_sdw3. Low-pass sequencing of selected BAC clones from these barley contigs exhibited a substantially lower gene frequency per physical distance and the presence of additional non-colinear genes. Four candidate genes for sdw3 were identified within barley BAC sequences that either co-segregated with the gene sdw3 or were located adjacent to these co-segregating genes. Identification of genic sequences in the sdw3 context provides tools for marker-assisted selection. Eventual identification of the actual gene will contribute new information for a basic understanding of the mechanisms underlying growth regulation in barley.

Indexed as

Chromosome MappingGenes, PlantSyntenyBase SequenceBrachypodiumChromosomes, Artificial, BacterialChromosomes, PlantGenetic MarkersGenome, PlantGenotypeGibberellinsHordeumMolecular Sequence DataOryzaPlant Growth RegulatorsPolymorphism, GeneticGenetic MarkersGibberellinsPlant Growth Regulators

Identifiers

PMID20464438
OpenAlexW2116031051

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.