ArticleChemical communications (Cambridge, England)2010
Antibiotic selectivity for prokaryotic vs. eukaryotic decoding sites.
Article in Chemical communications (Cambridge, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 24 citations in OpenAlex.
- Isomorphic Fluorescent Nucleosides.Accounts of chemical research · 2024Article
- Synthesis and antibacterial activity of 2-benzylidene-3-oxobutanamide derivatives against resistant pathogens.RSC medicinal chemistry · 2023Article
- Multifunctional Neomycin-Triazine-Based Cationic Lipids for Gene Delivery with Antibacterial Properties.Bioconjugate chemistry · 2021Article
- Translational readthrough-promoting drugs enhance pseudoknot-mediated suppression of the stop codon at the Moloney murine leukemia virus gag–pol junction.The Journal of general virology · 2015Article
- Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Singly modified amikacin and tobramycin derivatives show increased rRNA A-site binding and higher potency against resistant bacteria.ChemMedChem · 2014Article
- Enzymatic interconversion of isomorphic fluorescent nucleosides: adenosine deaminase transforms an adenosine analogue into an inosine analogue.Angewandte Chemie (International ed. in English) · 2013Article
- Polymyxins and analogues bind to ribosomal RNA and interfere with eukaryotic translation in vitro.Chembiochem : a European journal of chemical biology · 2013Article
- Direct observation of aminoglycoside-RNA binding by localized surface plasmon resonance spectroscopy.Analytical chemistry · 2013Article
- Selectively guanidinylated aminoglycosides as antibiotics.ChemMedChem · 2012Article
- Design, synthesis, and spectroscopic properties of extended and fused pyrrolo-dC and pyrrolo-C analogs.Organic letters · 2012Article
- Emissive RNA alphabet.Journal of the American Chemical Society · 2011Article
- A boost for the emerging field of RNA nanotechnology.ACS nano · 2011Article
- Fluorescent ribonucleoside as a FRET acceptor for tryptophan in native proteins.Journal of the American Chemical Society · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
A FRET assembly reports antibiotic affinities to two different RNA targets. A binder was labeled with a fluorophore that acts both as an acceptor for the emissive nucleoside on the bacterial A-site and a donor fluorophore for the terminally-labeled human A-site. Unlabeled drugs were used to dissociate the labeled antibiotic.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.