Evidence map›Paper›PMID 20463155›Full record

ArticleJournal of clinical microbiology2010

Geosmithia argillacea: an emerging pathogen in patients with cystic fibrosis.

Sandrine Giraud, Marc Pihet, Bienvenue Razafimandimby, Jacqueline Carrère, Nicolas Degand, Laurent Mely, Loïc Favennec, Eric Dannaoui, Jean-Philippe Bouchara, Alphonse Calenda

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 72 citations in OpenAlex.

  1. SystemicMedical mycology case reports · 2026
    Article
  2. Medical mycology case reports · 2025
    Article
  3. Review
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  6. DisseminatedJournal of fungi (Basel, Switzerland) · 2021
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  14. SystemicJMM case reports · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Sandrine GiraudGroupe d'Etude des Interactions Hôte-Pathogène, UPRES-EA 3142, Université d'Angers, Angers, France. sandrine.giraud@univ-angers.fr
Marc Pihet
Bienvenue Razafimandimby
Jacqueline Carrère
Nicolas Degand
Laurent Mely
Loïc Favennec
Eric Dannaoui
Jean-Philippe Bouchara
Alphonse Calenda
Université d'Angers · FRHôpital Renée Sabran · FRCentre Hospitalier Universitaire d'Angers · FRHôpital Charles-Nicolle · FRHôpital Européen Georges-Pompidou · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report eight cases of airway colonization by Geosmithia argillacea in patients with cystic fibrosis. This filamentous fungus, resembling members of the genera Penicillium and Paecilomyces, was identified by molecular analysis. All patients carried a mutation on each CFTR (cystic fibrosis transmembrane conductance regulator) allele, with at least one copy of the F508del mutation. The first isolation of this fungus occurred from F508del-homozygous patients at a younger age than in F508del-heterozygous patients. Before recovery of G. argillacea, all patients were treated with itraconazole; two of them had also received voriconazole for an Aspergillus fumigatus infection. However, antifungal susceptibility patterns showed high MICs of voriconazole for all isolates, and high MICs of amphotericin B and itraconazole for the majority of them, but mostly low minimum effective concentrations (MECs) of caspofungin. The appearance and persistence of G. argillacea in the airways were not associated with exacerbation of the disease. However, the clinical implications of G. argillacea, particularly in immunocompromised patients, remain a concern, particularly given recent observations suggesting that this fungus may also cause disseminated infections.

Indexed as

AdolescentAdultAntifungal AgentsBodily SecretionsChildCommunicable Diseases, EmergingCystic FibrosisEurotialesFemaleHumansImmunocompromised HostLungLung Diseases, FungalMaleMicrobial Sensitivity TestsMiddle AgedAntifungal Agents

Identifiers

PMID20463155
PMCPMC2897494
OpenAlexW2147301783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.