Evidence map›Paper›PMID 20461725›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2010

Mesoporous silica nanoparticles facilitate delivery of siRNA to shutdown signaling pathways in mammalian cells.

Christopher Hom, Jie Lu, Monty Liong, Hanzhi Luo, Zongxi Li, Jeffrey I Zink, Fuyuhiko Tamanoi

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Targeted nanodelivery systems for personalized cancer therapy.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024
    Review
  10. Article
  11. Review
  12. Nanoparticle-Based Interventions for Liver Transplantation.International journal of molecular sciences · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. AntisenseInternational journal of nanomedicine · 2022
    Article

14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christopher HomDepartment of Microbiology, Immunology, and Molecular Genetics California NanoSystems Institute, JCCC University of California, Los Angeles 609 Charles E. Young Drive East, Los Angeles, CA 90095, USA.
Jie Lu
Monty Liong
Hanzhi Luo
Zongxi Li
Jeffrey I Zink
Fuyuhiko Tamanoi

Funding

STRUCTURAL &FUNCTIONAL ANALYSES OF YEAST RAS PROTEINSR01CA041996 · NCI · UNIVERSITY OF CHICAGO · PI TAMANOI, FUYUHIKO · 1985 to 2014
$4.6M
Nanovalve Platform: Targeted, Controlled, Release of Anticancer DrugsR01CA133697 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI NEL, ANDRE ELIAS, STODDART, JAMES FRASER · 2010 to 2014
$2.1M
NCI NIH HHS CA 133697NCI NIH HHS CA41996NCI NIH HHS R01 CA041996NCI NIH HHS R01 CA133697
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsDrug CarriersGene SilencingHumansMaterials TestingNanoparticlesParticle SizePorosityRNA, Small InterferingSignal TransductionSilicon DioxideTransfectionDrug CarriersRNA, Small InterferingSilicon Dioxide

Identifiers

PMID20461725
PMCPMC2953950

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.